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Thiamazole, also known as methimazole, is a medication used to treat hyperthyroidism. [2] This includes Graves disease , toxic multinodular goiter , and thyrotoxic crisis . [ 2 ] It is taken by mouth. [ 2 ]
The most common drugs in this class are thioamides, which include propylthiouracil, methimazole and its prodrug carbimazole. Additionally, propylthiouracil may reduce the de-iodination of thyroxine (T 4) into triiodothyronine (T 3) in peripheral tissues. [2] Lugol's iodine is used to temporarily block thyroid hormone synthesis before surgeries. [3]
Price monitoring is the systematic process of observing and tracking the prices of commodities or securities to ensure they do not fall below a predetermined threshold. This activity is essential for organizations aiming to maintain stability in market prices and protect against significant fluctuations that could adversely affect economic balance. [1]
The online shopping gods work in mysterious ways. Sometimes, they reward you with an unbelievable deal. Other times, they make sure the one thing you desperately want is always out of stock.
A systematic review from 2016 found that metamizole significantly increased the relative risk of upper gastrointestinal bleeding, by a factor of 1.4–2.7 times. [31] A study by one of the manufacturers of the drug found the risk of agranulocytosis within the first week of treatment to be a 1.1 in a million, versus 5.9 in a million for diclofenac.
Carbimazole is a pro-drug as after absorption it is converted to the active form, methimazole. Methimazole prevents thyroid peroxidase enzyme from iodinating and coupling the tyrosine residues on thyroglobulin, hence reducing the production of the thyroid hormones T 3 and T 4 . It is on the World Health Organization's List of Essential Medicines.
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"Cool for Cats" is a song by English rock band Squeeze, released as the second single from their album of the same name. The song features a rare lead vocal performance from cockney-accented Squeeze lyricist Chris Difford , one of the only two occasions he sang lead on a Squeeze single A-side (the other was 1989's " Love Circles ").
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