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Ventral midline symptoms may also occur. Lesions around the ears and head are also common. These lesions are characterised by intense pruritus (itching), which results in rubbing and considerable self-trauma. This damage is caused by the horse violently rubbing itself against objects, and causes: broken hairs; broken and sometimes bleeding skin
Mohler, John R., Dourine of horses – its cause and suppression (1911) Covering sickness, or dourine (French, from the Arabic darina, meaning mangy (said of a female camel), feminine of darin, meaning dirty), [1] is a disease of horses and other members of the family Equidae.
Horses heterozygous for the Ile118Lys mutation on the equine EDNRB gene—carriers of lethal white syndrome—usually exhibit a white-spotting pattern called "frame", or "frame overo". [5] [7] [9] [13] Frame is characterized by jagged, sharply defined, horizontally oriented white patches that run along the horse's neck, shoulder, flank, and ...
It is a rare blood condition in which the β-pyrrole ring of the hemoglobin molecule has the ability to bind irreversibly to any substance containing a sulfur atom. [ 1 ] [ 2 ] When hydrogen sulfide (H 2 S) (or sulfide ions ) and ferrous ions combine in the heme of hemoglobin, the blood is thus incapable of transporting oxygen to the tissues.
The skin is loose, and hyper-elastic in affected horses. This collagen based abnormality affects their heart valves too and their mechanical properties are found to be inferior to native horses. [2] Symptoms typically don’t appear until the horse is subjected to pressure or injury on their back, neck or hips, usually around two years of age.
However, any horse that can store excess amounts of glycogen, usually genetic, can develop this form of ER. [1] Recurrent Exertional Rhabdomyolysis (RER) is commonly found in breeds that are high strung such as Arabians and thoroughbreds. However, any horse can develop this type of ER if it displays abnormal muscle contractions. [1]
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The most common symptoms of EPM are ataxia, general weakness with muscle spasticity. However, this is not specific to EPM and is common in many other neurological disorders. Clinical signs among horses with EPM include a wide array of symptoms that may result from primary or secondary problems.