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After the development of kidney failure patients may get deposits of oxalate in the bones, joints and bone marrow. Severe cases may develop haematological problems such as anaemia and thrombocytopaenia. The deposition of oxalate in the body is sometimes called "oxalosis" to be distinguished from "oxaluria" which refers to oxalate in the urine.
Oxalobacter formigenes is a Gram negative oxalate-degrading anaerobic bacterium that was first isolated from the gastrointestinal tract of a sheep in 1985. [1] To date, the bacterium has been found to colonize the large intestines of numerous vertebrates, including humans, and has even been isolated from freshwater sediment. [2]
Oxalate also forms coordination compounds where it is sometimes abbreviated as ox. It is commonly encountered as a bidentate ligand. When the oxalate chelates to a single metal center, it always adopts the planar conformation. As a bidentate ligand, it forms a 5-membered MC 2 O 2 ring. An illustrative complex is potassium ferrioxalate, K 3 [Fe ...
The symptoms of early and late dumping syndrome are different and vary from person to person. Early dumping syndrome symptoms may include: [1] nausea; vomiting; abdominal pain and cramping; diarrhea; feeling uncomfortably full or bloated after a meal; sweating; weakness; dizziness; flushing, or blushing of the face or skin; rapid or irregular ...
Oxalate oxidase (Enzyme Commission number EC 1.2.3.4 [2] )occurs mainly in plants. It can degrade oxalic acid into carbon dioxide and hydrogen peroxide. [3]Oxalate decarboxylase (OXDC,EC 4.1.1.2) is a kind of oxalate degrading enzyme containing Mn 2+, [4] found mainly in fungi or some bacteria.
The term nephrocalcinosis is used to describe the deposition of both calcium oxalate and calcium phosphate. [1] It may cause acute kidney injury. It is now more commonly used to describe diffuse, fine, renal parenchymal calcification in radiology. [2] It is caused by multiple different conditions and is determined by progressive kidney dysfunction.
Some of the oxalate in urine is produced by the body. Calcium and oxalate in the diet play a part but are not the only factors that affect the formation of calcium oxalate stones. Dietary oxalate is an organic ion found in many vegetables, fruits, and nuts. Calcium from bone may also play a role in kidney stone formation.
As many as 39% of the children had resolution of symptoms immediately or within weeks of the diagnosis. Vomiting had resolved at the time of follow-up in 61% of the sample. Many children, including those in the remitted group, continued to have somatic symptoms such as headaches (in 42%) and abdominal pain (in 37%). [18]