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The Center for Stem Cell and Regenerative Medicine (CSCRM) is a medical research institution specializing in stem cell and other cell therapy research and treatments, located in Cleveland, Ohio. They specialize in basic and clinical research programs, biomedical and tissue engineering programs, and the development and administration of new ...
Ohio Agricultural Research and Development Center (OARDC) is the research institution of the Ohio State University College of Food, Agricultural, and Environmental Sciences. The center is home to research projects ranging from plant and animal sciences to human ecology and medicine, and includes branches across the state covering a total of ...
One significant cell-line cross contaminant is the immortal HeLa cell line. HeLa contamination was first noted in the early 1960s in non-human culture in the USA. Intraspecies contamination was discovered in nineteen cell lines in the seventies. In 1974, five human cell lines from the Soviet Union were found to be HeLa.
Ohio receives around $2.7 billion annually in federal R&D funds, ranking #9. [4] In 2005, it was ranked #4 in the country in industrial R&D activities, while the University of Dayton and Ohio State University ranked #2 and #3 nationally in total materials research. Ohio leads the nation in plastics and rubber research. [5]
To produce viral vaccines, candidate vaccine viruses are grown in mammalian, avian or insect tissue culture of cells with a finite lifespan. [5] These cells are typically Madin-Darby Canine Kidney cells, [6] but others are also used including monkey cell lines pMK and Vero and human cell lines HEK 293, MRC 5, Per.C6, PMK, and WI-38. [7]
Since the original CHO cell line was described in 1956, many variants of the cell line have been developed for various purposes. [10] [additional citation(s) needed] In 1957, CHO-K1 was generated from a single clone of CHO cells. [16] According to an industry source, however, scientist Theodore Puck first isolated CHO-K1 in 1968. [1]
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