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  2. List of benzimidazole opioids - Wikipedia

    en.wikipedia.org/wiki/List_of_benzimidazole_opioids

    Desnitazene (1-diethylaminoethyl-2-benzyl-benzimidazole) hydrogen 0.1 28787: 17817-67-3 Metodesnitazene (Metazene) 4-methoxy 1 26412: 14030-77-4 1071546-40-1 (HCl) Metodesnitazepyne: 4-methoxy Etodesnitazene (Etazene) 4-ethoxy 70 149797386: 14030-76-3 Etodesnitazepyne: 4-ethoxy 20 162623599: Etodesnitazepipne: 4-ethoxy 10 162623611: 102762-98-1 ...

  3. Etonitazene - Wikipedia

    en.wikipedia.org/wiki/Etonitazene

    The three component synthesis of the direct etonitazene precursor, 2-(4-Ethoxybenzyl)-5-nitro-1H-benzoimidazole, consists of a 2-Bromo- or 2-Iodo-5-nitro-phenylamine (1.0 molar equivalent), a 4-substituted benzaldehyde (1.2 equiv), and sodium azide (2 equiv). The 2-Halo-5-nitro-phenylamine requires a bromo or iodo group for optimal activity.

  4. Methylenedioxynitazene - Wikipedia

    en.wikipedia.org/wiki/Methylenedioxynitazene

    Methylenedioxynitazene (3',4'-Methylenedioxynitazene) is a benzimidazole derivative which has been sold as a designer drug over the internet and presumably has opioid effects. It is an analogue of etonitazene where the benzyl ring is substituted with a 3,4-methylenedioxy ring system rather than an ethoxy group. It was first reported in the UK ...

  5. Benzimidazole - Wikipedia

    en.wikipedia.org/wiki/Benzimidazole

    Benzimidazole is a base: C 6 H 4 N(NH)CH + H + → [C 6 H 4 (NH) 2 CH] + It can also be deprotonated with stronger bases: C 6 H 4 N(NH)CH + LiH → Li [C 6 H 4 N 2 CH] + H 2. The imine can be alkylated and also serves as a ligand in coordination chemistry. The most prominent benzimidazole complex features N-ribosyl-dimethylbenzimidazole, as ...

  6. Butonitazene - Wikipedia

    en.wikipedia.org/wiki/Butonitazene

    Butonitazene is a benzimidazole derivative with opioid effects, which has been sold over the internet as a designer drug.It has relatively low potency compared to many related compounds, and has generally been encountered as a component of mixtures with other substances rather than in its pure form.

  7. Mercaptobenzimidazole - Wikipedia

    en.wikipedia.org/wiki/Mercaptobenzimidazole

    It is the mercaptan of benzimidazole. It is a white solid that has been investigated as a corrosion inhibitor . The name is a misnomer because the compound is a thiourea , characterized with a short C=S bond length of 169 pm. [ 1 ] A similar situation applies to 2-mercaptoimidazole, which is also a thiourea properly called 2-imidazolidinethione ...

  8. Benznidazole - Wikipedia

    en.wikipedia.org/wiki/Benznidazole

    Benznidazole is an antiparasitic medication used in the treatment of Chagas disease. [2] While it is highly effective in early disease, the effectiveness decreases in those who have long-term infection. [3] It is the first-line treatment given its moderate side effects compared to nifurtimox. [1] It is taken by mouth. [2] Side effects are ...

  9. N-Desethylisotonitazene - Wikipedia

    en.wikipedia.org/wiki/N-Desethylisotonitazene

    N-Desethylisotonitazene (norisotonitazene) is a benzimidazole opioid with potent analgesic effects which has been sold as a designer drug.It was first identified in 2023 as an active metabolite of the closely related compound isotonitazene, and was found to have similar potency.