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  2. List of herbs with known adverse effects - Wikipedia

    en.wikipedia.org/wiki/List_of_herbs_with_known...

    "Potentiates digitalis activity, increases coronary dilation effects of theophylline, caffeine, papaverine, sodium nitrate, adenosine and epinephrine, increase barbiturate-induced sleeping times" [3] Horse chestnut: conker tree, conker Aesculus hippocastanum: Liver toxicity, allergic reaction, anaphylaxis [3] Kava: awa, kava-kava [4] Piper ...

  3. Kavalactone - Wikipedia

    en.wikipedia.org/wiki/Kavalactone

    Kavalactones are a class of lactone compounds found in kava roots and Alpinia zerumbet (shell ginger). [1] and in several Gymnopilus, Phellinus and Inonotus fungi. [2] Some kavalactones are bioactive. They are responsible for the psychoactive, analgesic, euphoric and sedative effects of kava. [3] [4]

  4. Kavain - Wikipedia

    en.wikipedia.org/wiki/Kavain

    Kavain has anticonvulsive properties, attenuating vascular smooth muscle contraction through interactions with voltage-dependent Na + and Ca 2+ channels. [1] How this effect is mediated, and to what extent this mechanism is involved in the anxiolytic and analgesic effects of kavalactones on the central nervous system, is unknown.

  5. Kava - Wikipedia

    en.wikipedia.org/wiki/Kava

    Kava prepared as described above is much more potent than processed kava. Chewing produces the strongest effect because it produces the finest particles. Fresh, undried kava produces a stronger beverage than dry kava. The strength also depends on the species and techniques of cultivation.

  6. Methysticin - Wikipedia

    en.wikipedia.org/wiki/Methysticin

    Research suggests that methysticin and the related compound dihydromethysticin have CYP1A1 inducing effects which may be responsible for their toxicity. [2] Additionally, methysticin has been shown to potentiate GABA A receptor activity, contributing to the overall anxiolytic profile of the kava plant.

  7. List of cytochrome P450 modulators - Wikipedia

    en.wikipedia.org/wiki/List_of_cytochrome_P450...

    This is a list of cytochrome P450 modulators, or inhibitors and inducers of cytochrome P450 enzymes. Enzyme ... Kava Peppermint Turmeric CYP2A6: CYP2B6: See also.

  8. Cardiac physiology - Wikipedia

    en.wikipedia.org/wiki/Cardiac_physiology

    Cardiac physiology or heart function is the study of healthy, unimpaired function of the heart: involving blood flow; myocardium structure; the electrical conduction system of the heart; the cardiac cycle and cardiac output and how these interact and depend on one another.

  9. Alcoholic cardiomyopathy - Wikipedia

    en.wikipedia.org/wiki/Alcoholic_cardiomyopathy

    Persons with congestive heart failure may be considered for surgical insertion of an ICD or a pacemaker which can improve heart function. In cases where the heart failure is irreversible and worsening, heart transplant may be considered. [7] Treatment will possibly prevent the heart from further deterioration, and the cardiomyopathy is largely ...

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