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  2. Immune reconstitution inflammatory syndrome - Wikipedia

    en.wikipedia.org/wiki/Immune_reconstitution...

    Immune reconstitution inflammatory syndrome (IRIS) is a condition seen in some cases of HIV/AIDS or immunosuppression, in which the immune system begins to recover, but then responds to a previously acquired opportunistic infection with an overwhelming inflammatory response that paradoxically makes the symptoms of infection worse.

  3. Opportunistic infection - Wikipedia

    en.wikipedia.org/wiki/Opportunistic_infection

    An opportunistic infection is a serious infection caused by pathogens (bacteria, fungi, parasites or viruses) that under normal conditions, such as in humans with uncompromised immune systems, would cause a mild infection or no infection at all.

  4. Pathophysiology of HIV/AIDS - Wikipedia

    en.wikipedia.org/wiki/Pathophysiology_of_HIV/AIDS

    HIV seeks out and destroys CCR5 expressing CD4 + cells during acute infection. A vigorous immune response eventually controls the infection and initiates the clinically latent phase. However, CD4 + T cells in mucosal tissues remain depleted throughout the infection, although enough remain to initially ward off life-threatening infections.

  5. WHO disease staging system for HIV infection and disease

    en.wikipedia.org/wiki/WHO_Disease_Staging_System...

    Most of these conditions are opportunistic infections that are easily treated in healthy people. The staging system is different for adults and adolescents and children. [2] Stage I: HIV disease is asymptomatic and not categorized as AIDS. Stage II: include minor mucocutaneous manifestations and recurrent upper respiratory tract infections.

  6. HIV - Wikipedia

    en.wikipedia.org/wiki/HIV

    The human immunodeficiency viruses (HIV) are two species of Lentivirus (a subgroup of retrovirus) that infect humans.Over time, they cause acquired immunodeficiency syndrome (AIDS), [1] [2] a condition in which progressive failure of the immune system allows life-threatening opportunistic infections and cancers to thrive. [3]

  7. Signs and symptoms of HIV/AIDS - Wikipedia

    en.wikipedia.org/wiki/Signs_and_symptoms_of_HIV/AIDS

    Unexplained chronic diarrhea in HIV infection is due to many possible causes, including common bacterial (Salmonella, Shigella, Listeria or Campylobacter) and parasitic infections; and uncommon opportunistic infections such as cryptosporidiosis, microsporidiosis, Mycobacterium avium complex (MAC) and viruses, [21] astrovirus, adenovirus ...

  8. Diagnosis of HIV/AIDS - Wikipedia

    en.wikipedia.org/wiki/Diagnosis_of_HIV/AIDS

    Declining CD4 T-cell counts are considered to be a marker of progression of HIV infection. A normal CD4 count can range from 500 cells/mm3 to 1000 cells/mm3. In HIV-positive people, AIDS is officially diagnosed when the count drops below 200 cells/μL or when certain opportunistic infections occur. This use of a CD4 count as an AIDS criterion ...

  9. NIAID ChemDB - Wikipedia

    en.wikipedia.org/wiki/NIAID_ChemDB

    The ChemDB HIV, Opportunistic Infection and Tuberculosis Therapeutics Database is a publicly available tool developed by the National Institute of Allergy and Infectious Diseases to compile preclinical data on small molecules with potential therapeutic action against HIV/AIDS and related opportunistic infections. [1]

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