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A common side effect of prostaglandin E 2 is its effect on gastrointestinal smooth muscle resulting in nausea, vomiting and diarrhea. Other side effects include headache, shivering, and chills. [4] The suppository form of prostaglandin E 2 is associated with increased severity of these symptoms.
Misoprostol is also used to prevent and treat post-partum bleeding. Orally administered misoprostol was marginally less effective than oxytocin. [45] The use of rectally administered misoprostol is optimal in cases of bleeding; it was shown to be associated with lower rates of side effects compared to other routes.
When injected into the penis for erectile dysfunction; side effects may include penile pain, bleeding at the site of injection, and prolonged erection (priapism). [2] Prostaglandin E 1 was isolated in 1957 and approved for medical use in the United States in 1981. [2] [6] Misoprostol has various obstetric uses.
Other adverse effects may include nausea, vomiting, fever, chills, diarrhea, headache, dizziness, warmth or hot flashes. [50] [43] [20] When used inside the vagina, misoprostol tends to have fewer gastrointestinal side effects. [6] Nonsteroidal anti-inflammatory medications such as ibuprofen reduce pain with medication abortion.
Diclofenac, sold under the brand name Voltaren among others, is a nonsteroidal anti-inflammatory drug (NSAID) used to treat pain and inflammatory diseases such as gout. [6] [9] It can be taken orally (swallowed by mouth), inserted rectally as a suppository, injected intramuscularly, injected intravenously, applied to the skin topically, or through eye drops.
If you’re in the clear to take berberine, there are a few potential side effects to consider. Berberine can upset your gastrointestinal system, causing symptoms like: nausea, diarrhea ...
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Prostaglandin analogues such as misoprostol are used in treatment of duodenal and gastric ulcers. [2] Misoprostol and other prostaglandin analogues protect the lining of the gastrointestinal tract from harmful stomach acid and are especially indicated for the elderly on continuous doses of NSAIDs .