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Famotidine, sold under the brand name Pepcid among others, is a histamine H 2 receptor antagonist medication that decreases stomach acid production. [4] It is used to treat peptic ulcer disease , gastroesophageal reflux disease , and Zollinger-Ellison syndrome . [ 4 ]
Cimetidine was the prototypical histamine H 2 receptor antagonist from which later drugs were developed. Cimetidine was the culmination of a project at Smith, Kline & French (SK&F; now GlaxoSmithKline) by James W. Black, C. Robin Ganellin, and others to develop a histamine receptor antagonist that would suppress stomach acid secretion.
Ibuprofen/famotidine, sold under the brand name Duexis, is a fixed-dose combination medication used for the treatment of rheumatoid arthritis and osteoarthritis. [1] It contains ibuprofen , a nonsteroidal anti-inflammatory drug (NSAID) and famotidine, a histamine H2-receptor antagonist .
Subsequent to the introduction onto the U.S. drug market, two other H 2 receptor antagonists were approved, ranitidine (Zantac, Glaxo Labs) and famotidine (Pepcid, Yamanouchi, Ltd.) Cimetidine became the first drug ever to reach more than $1 billion a year in sales, thus making it the first blockbuster drug. [citation needed]
Too bad, otherwise it would be a GREAT idea to take for example 20mg of Famotidine with 400mg or 800mg ibuprofen painkiller. Unless one knows in advance that one has a headache and takes Famotidine first. As Ibuprofen increases stomach bleeding risk, Famotidine reduces this risk by about 50%? 91.159.189.212 14:34, 3 June 2023 (UTC)
This page was last edited on 14 April 2016, at 06:04 (UTC).; Text is available under the Creative Commons Attribution-ShareAlike 4.0 License; additional terms may ...
What is the 30-30-30 method and does it work for weight loss? Experts discuss the benefits and risks of this new diet and fitness trend.
Mucosal disruption in acid peptic disease patients can be caused by infection, barrier disruption, or gastric acid hypersecretion.Acid peptic diseases can arise due to various risk factors such as Helicobacter pylori infection, alcoholism, tobacco use, cocaine and amphetamine use, nonsteroidal anti-inflammatory drug use (NSAIDs), fasting, Zollinger-Ellison syndrome, angiogenesis inhibitor ...
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