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BCS classes. According to the Biopharmaceutics Classification System (BCS) drug substances are classified to four classes upon their solubility and permeability: [1] Class I – high permeability, high solubility. Example: metoprolol, paracetamol [2] Those compounds are well absorbed and their absorption rate is usually higher than excretion.
Aceclofenac falls under the BCS Class II, poorly soluble and highly permeable drug. [ 5 ] Aceclofenac works by inhibiting the action of cyclooxygenase (COX) that is involved in the production of prostaglandins (PG) which is accountable for pain, swelling, inflammation and fever.
This is the list of Schedule II controlled substances in the United States as defined by the Controlled Substances Act. [1] The following findings are required, by section 202 of that Act, for substances to be placed in this schedule: The drug or other substance has a high potential for abuse.
Author: pwei: Short title: Library of Congress Classification Outline; Date and time of digitizing: 16:07, 12 March 2003: File change date and time: 13:31, 22 November 2010
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The ATC classification system is a strict hierarchy, [5] meaning that each code necessarily has one and only one parent code, except for the 14 codes at the topmost level which have no parents. The codes are semantic identifiers, [ 5 ] meaning they depict information by themselves beyond serving as identifiers (namely, the codes depict ...
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As of mid-2006, dacarbazine is commonly used as a single agent in the treatment of metastatic melanoma, [5] [6] and as part of the ABVD chemotherapy regimen to treat Hodgkin's lymphoma, [7] and in the MAID regimen for sarcoma.