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The systems of the body most affected by chemotherapy drugs include visual and semantic memory, attention and motor coordination and executive functioning. [9] [10] These effects can impair a chemotherapy patient's ability to understand and make decisions regarding treatment, perform in school or employment and can reduce quality of life. [10]
Motor and autonomic symptoms are less frequent but possible. Symptoms may start days after the patient receives their first dose of chemotherapy, are dose dependent, and tend to improve after completion of treatment. However, in some cases, symptoms can persist six months or later following the completion of chemotherapy. [8]
High-dose estrogen therapy is used in the treatment of prostate cancer. [52] Estrogens that have been used include diethylstilbestrol , fosfestrol , ethinylestradiol , ethinylestradiol sulfonate , polyestradiol phosphate , and estradiol undecylate , as well as the dual estrogenic and cytostatic agent estramustine phosphate .
5-HT 3 antagonists are most effective in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV), especially that caused by highly emetogenic drugs such as cisplatin; when used for this purpose, they may be given alone or, more frequently, with a glucocorticoid, usually dexamethasone.
After being diagnosed with stage 2 breast cancer earlier this year, Jill underwent a double mastectomy and had 17 lymph nodes removed before starting aggressive chemotherapy. After finishing ...
A chemotherapy regimen is a regimen for chemotherapy, defining the drugs to be used, their dosage, the frequency and duration of treatments, and other considerations. In modern oncology, many regimens combine several chemotherapy drugs in combination chemotherapy. The majority of drugs used in cancer chemotherapy are cytostatic, many via ...
Elsewhere during her visit, Kate shared more details on her chemo, including that she had a port to administer the therapy. “I got so attached to it,” the Princess said of her port.
In conventional chemotherapy, a dose close to the maximum tolerated dose is administered in a bolus manner to achieve cytotoxic effects on tumor cells. [5] However, the side effects are often significant as the cytotoxic agents also kill the fast-dividing cells normally present in the body, such as bone marrow cells and epithelial cells of the gastrointestinal tract. [6]