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A lentigo (/ l ɛ n ˈ t aɪ ɡ oʊ /) (plural lentigines, / l ɛ n ˈ t ɪ dʒ ɪ n iː z /) is a small pigmented spot on the skin with a clearly defined edge, surrounded by normal-appearing skin. It is a harmless (benign) hyperplasia of melanocytes which is linear in its spread.
Lentigo maligna is a histopathological variant of melanoma in situ. [6] Lentigo maligna is sometimes classified as a very early melanoma, [7] and sometimes as a precursor to melanoma. [8] When malignant melanocytes from a lentigo maligna have invaded below the epidermis, the condition is termed lentigo maligna melanoma. [2]
Lentigo simplex is the most common form of lentigo. [ 2 ] : 29 A single lesion or multiple lesions (lentigines) may be present at birth or more commonly first develop in early childhood. Lentigo simplex is not induced by sun exposure, and it is not associated with any medical diseases or conditions.
Lentiginosis refers to the presence of lentigines in large numbers or in a distinctive configuration. [1] These are spotted areas created by accumulation in the skin due to sun exposure.
Ann Arbor is a city in and the county seat of Washtenaw County in the U.S. state of Michigan.Founded in 1824 by John Allen and Elisha Rumsey, it was named after the wives of the village's founders, both named Ann, and the stands of bur oak trees they found there.
Histology slide of a solar lentigo. Differently from the melanotic nevi and the verrucous nevi on the skin, age spots change in color and in shape with time. Wang-Michelitsch and Michelitsch propose a hypothesis inspired by their misrepair-accumulation aging theory [12] for the development of age spots. [13]
Ink spot lentigo is a cutaneous condition characterized by skin lesions commonly occurring on the shoulders. [1] These lesions often cause alarm but are benign. They are an indication of excessive sun exposure so although ink spot lentigo is not premalignant, people with several of them maybe at increased risk of skin cancer due to UV damage.
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