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Testosterone is the primary male sex hormone and androgen in males. [4] In humans, testosterone plays a key role in the development of male reproductive tissues such as testicles and prostate, as well as promoting secondary sexual characteristics such as increased muscle and bone mass, and the growth of body hair.
A hilar cell tumor is an androgen-producing ovarian tumor that is most commonly found in older women and often leads to the development of male sex characteristics. The tumor tends to occur around the region of the ovary where the blood vessels enter the organ, known as the hilum. This type of tumor tends to be small in size and in most cases ...
The masculinization of the embryonic reproductive structures occurs as a result of testosterone secreted by the embryonic testes. Testosterone, however, is not the active agent within these organs. Once inside the target cells, testosterone is converted by means of an enzyme called 5α-reductase into the dihydrotestosterone (DHT).
Late-onset hypogonadism (LOH) or testosterone deficiency syndrome (TDS) [1] [2] is a term for a condition in older men characterized by measurably low testosterone levels and clinical symptoms mostly of a sexual nature, including decreased desire for mating, fewer spontaneous erections, and erectile dysfunction. [3]
Low testosterone can be identified through a simple blood test performed by a laboratory, ordered by a health care provider. Blood for the test must be taken in the morning hours, when levels are highest, as levels can drop by as much as 13% during the day and all normal reference ranges are based on morning levels.
The researchers, who relied on animal testing to conduct the study, found the opposite was true when it came to testosterone, the male hormone produced mainly in the testes, and testicle size.
Intratesticular testosterone levels are 20–100 or 50–200 times higher than the concentration found in blood, although there is variation over a 5- to 10-fold range amongst healthy men. [29] [30] Testosterone production does not remain constant throughout the day, but follows a circadian rhythm. The maximum peak of testosterone occurs at 8 a ...
In mice, prenatal testosterone transfer causes higher blood concentrations of testosterone in 2M females when compared to 1M or 0M females. [6] This has a variety of consequences on later female behavior, physiology, and morphology. Below is a table comparing physiological, morphological, and behavioral differences of 0M and 2M female mice. [1]
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