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Merkel cell carcinoma (MCC) is a rare and aggressive skin cancer occurring in about three people per million members of the population. [1] It is also known as cutaneous APUDoma, primary neuroendocrine carcinoma of the skin, primary small cell carcinoma of the skin, and trabecular carcinoma of the skin. [ 2 ]
Cancer Research UK has recently warned that skin cancer cases are set to rise by half by 2040
“Margaritaville” singer Jimmy Buffet died of Merkel cell carcinoma on Sept. 1. Merkel cell carcinoma is a rare and aggressive form of skin cancer. Experts stress the importance of early detection.
More than 3.5 million cases of skin cancer are diagnosed annually in the United States, which makes it the most common form of cancer in that country. One in five Americans will develop skin cancer at some point of their lives. The most common form of skin cancer is basal-cell carcinoma, followed by squamous cell carcinoma.
As with all skin cancers, sun exposure is a risk factor, as is a compromised immune system and previous history of skin cancer.
Retifanlimab, sold under the brand name Zynyz, is an anti-cancer medication used for the treatment of Merkel cell carcinoma. [1] Retifanlimab is a programmed death receptor-1 (PD-1)–blocking monoclonal antibody .
Merkel cell carcinoma accounts for fewer than 1% of all skin cancers — but when it metastasizes it often turns deadly. ... Sign in. Mail. 24/7 Help. For premium support please call: 800-290-4726 ...
The US Food and Drug Administration (FDA) approved it in March 2017, for the treatment of Merkel-cell carcinoma, [7] an aggressive type of skin cancer. The EMA approved it in September 2017, for the same indication. [9] This is the first FDA-approved treatment for metastatic Merkel-cell carcinoma, a rare, aggressive form of skin cancer. [7]