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A major influence on the theory was Emil Kraepelin, lining up degeneration theory with his psychiatry practice. The central idea of this concept was that in "degenerative" illness, there is a steady decline in mental functioning and social adaptation from one generation to the other.
Emil Wilhelm Georg Magnus Kraepelin (/ ˈ k r ɛ p əl ɪ n /; German: [ˈeːmiːl 'kʁɛːpəliːn]; 15 February 1856 – 7 October 1926) was a German psychiatrist. H. J. Eysenck's Encyclopedia of Psychology identifies him as the founder of modern scientific psychiatry, psychopharmacology and psychiatric genetics.
Emil Kraepelin (1856–1926). The Kraepelinian dichotomy is the division of the major endogenous psychoses into the disease concepts of dementia praecox, which was reformulated as schizophrenia by Eugen Bleuler by 1908, [1] [2] and manic-depressive psychosis, which has now been reconceived as bipolar disorder. [3]
Descriptive psychiatry is based on the study of observable symptoms and behavioral phenomena rather than underlying psychodynamic processes. In descriptive psychiatry, the clinical psychiatrist focuses on empirically observable behaviors and conditions, such as words spoken or actions taken.
Later, Kraepelin's stance changed, broadly in line with the results of a study he had commissioned by his colleague Georges L. Dreyfus: by the time of the publication of the eighth edition of his textbook in 1913, he had incorporated involutional melancholia under the general heading of 'manic-depressive illness'. [1] [3]
Kraepelin initially was very attracted to psychology and ignored the ideas of anatomical psychiatry. [50] Following his appointment to a professorship of psychiatry and his work in a university psychiatric clinic, Kraepelin's interest in pure psychology began to fade and he introduced a plan for a more comprehensive psychiatry. [51]
The presence of neurofibrillary tangles in the brain is one of the key hallmarks of Alzheimer’s disease. These irregular clumps of protein are closely associated with disease progression.
German Physician Emil Kraepelin was more interested in the causes of mental disorders and potential classifications rather than focusing on and attempting to treating symptoms of mental disorders. This led to the classification of manic depression and Schizophrenia, as well as the start of a framework for classifying other disorders.