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Acetamide (systematic name: ethanamide) is an organic compound with the formula CH 3 CONH 2. It is an amide derived from ammonia and acetic acid. It finds some use as a plasticizer and as an industrial solvent. [5] The related compound N,N-dimethylacetamide (DMA) is more widely used, but it is not
It is used as a biochemical tool in the study of carcinogenesis. It induces tumors in a number of species in the liver, bladder and kidney. The metabolism of this compound in the body by means of biotransformation reactions is the key to its carcinogenicity . 2-AAF is a substrate for cytochrome P-450 (CYP) enzyme, which is a part of a super ...
A notable method for synthesizing acetamidomalon ester is described in a 1950 patent, [1] which cites a procedure previously featured in Organic Syntheses. [2] The synthesis procedure involves the preparation of malonic acid diethyl ester in acetic acid combined with sodium nitrite (NaNO 2), resulting in diethyl isonitrosomalonate (also known as α-oximinomalonic acid diethyl ester).
Acetamide; Dichloroacetamide; N-Chlorosuccinimide; ... Chloroacetamide has been used as an herbicide, [5] preservative. [6] and in the manufacturing of pharmaceuticals.
Acetanilide can be produced by reacting acetic anhydride with aniline: [7]. C 6 H 5 NH 2 + (CH 3 CO) 2 O → C 6 H 5 NHCOCH 3 + CH 3 COOH. The preparation used to be a traditional experiment in introductory organic chemistry lab classes, [8] but it has now been widely replaced by the preparation of either paracetamol or aspirin, both of which teach the same practical techniques (especially ...
It can also be used to construct the amino acid alanine and can be converted into ethanol or lactic acid via fermentation. Pyruvic acid supplies energy to cells through the citric acid cycle (also known as the Krebs cycle) when oxygen is present ( aerobic respiration ), and alternatively ferments to produce lactate when oxygen is lacking.
Much of biochemistry deals with the structures, functions, and interactions of biological macromolecules such as proteins, nucleic acids, carbohydrates, and lipids. They provide the structure of cells and perform many of the functions associated with life. [6] The chemistry of the cell also depends upon the reactions of small molecules and ions.
This reagent is common in the laboratory; its use cogenerates acetic acid. [7] [10] Acetyl chloride. This reagent is also common in the laboratory, but its use cogenerates hydrogen chloride, which can be undesirable. [8] Ketene. At one time acetic anhydride was prepared by the reaction of ketene with acetic acid: [11]