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Asperger syndrome (AS), also known as Asperger's syndrome or Asperger's, is a diagnostic label that has been used to describe a neurodevelopmental disorder characterized by significant difficulties in social interaction and nonverbal communication, along with restricted, repetitive patterns of behavior and interests. [5]
Disorders formerly considered distinct, but now diagnosed as autism spectrum disorder, include: Asperger syndrome – a previously diagnosed form of autism often applied to people with a higher IQ who can have a less difficult time communicating with others and understanding concepts or phrases than other individuals with more severe autism. As ...
The DSM-V made a new, broad diagnosis in 2013 of autism spectrum disorder (ASD). This category contains the previous individual diagnoses of Autistic Disorder, Asperger's Syndrome, and other related developmental disorders. ASD is rated on levels of severity on a scale ranging from severe, through moderate, to mild based on clinical ...
[283] [284] [285] Asperger syndrome was traditionally called "schizoid disorder of childhood". Genetic disorders – about 10–15% of autism cases have an identifiable Mendelian (single-gene) condition, chromosome abnormality, or other genetic syndromes. [286] Several metabolic defects, such as phenylketonuria, are associated with autistic ...
NF-1 is one of the most common genetic disorders and is not limited to any person's race or sex. NF-1 is an autosomal dominant disorder, which means that mutation or deletion of one copy (or allele) of the NF-1 gene is sufficient for the development of NF-1, although presentation varies widely and is often different even between relatives ...
One part of it identified a group of five children that might today be considered autistic. The paper was published in March 1938. [134] In 1939 and 1940, Dutch psychiatrist Alfons Chorus of Nijmegen's Pedological Institute published a pair of papers describing children that were autists and schizoid, which today would be considered autistic. [135]
Classic autism, also known as childhood autism, autistic disorder, or Kanner's syndrome, is a formerly diagnosed neurodevelopmental disorder first described by Leo Kanner in 1943. It is characterized by atypical and impaired development in social interaction and communication as well as restricted, repetitive behaviors, activities, and interests.
The amygdala, cerebellum, and many other brain regions have been implicated in autism. [15]Unlike some brain disorders which have clear molecular hallmarks that can be observed in every affected individual, such as Alzheimer's disease or Parkinson's disease, autism does not have a unifying mechanism at the molecular, cellular, or systems level.