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The double-helix model of DNA structure was first published in the journal Nature by James Watson and Francis Crick in 1953, [6] (X,Y,Z coordinates in 1954 [7]) based on the work of Rosalind Franklin and her student Raymond Gosling, who took the crucial X-ray diffraction image of DNA labeled as "Photo 51", [8] [9] and Maurice Wilkins, Alexander Stokes, and Herbert Wilson, [10] and base-pairing ...
Each end of the double helix has an exposed 5' phosphate on one strand and an exposed 3′ hydroxyl group (—OH) on the other. DNA is a long polymer made from repeating units called nucleotides. [6] [7] The structure of DNA is dynamic along its length, being capable of coiling into tight loops and other shapes. [8]
The pitch of a helix is the height of one complete helix turn, measured parallel to the axis of the helix. A double helix consists of two (typically congruent) helices with the same axis, differing by a translation along the axis. [3] A circular helix (i.e. one with constant radius) has constant band curvature and constant torsion. The slope of ...
In DNA double helix, the two strands of DNA are held together by hydrogen bonds. The nucleotides on one strand base pairs with the nucleotide on the other strand. The secondary structure is responsible for the shape that the nucleic acid assumes. The bases in the DNA are classified as purines and pyrimidines. The purines are adenine and guanine ...
From the very early stages of structural studies of DNA by X-ray diffraction and biochemical means, molecular models such as the Watson-Crick nucleic acid double helix model were successfully employed to solve the 'puzzle' of DNA structure, and also find how the latter relates to its key functions in living cells.
The Double Helix: A Personal Account of the Discovery of the Structure of DNA is an autobiographical account of the discovery of the double helix structure of DNA written by James D. Watson and published in 1968. It has earned both critical and public praise, along with continuing controversy about credit for the Nobel award and attitudes ...
The Double Helix: A Personal Account of the Discovery of the Structure of DNA. Atheneum. ISBN 978-0-689-70602-8. (first published in 1968) Wilkins, Maurice (2003). The Third Man of the Double Helix: The Autobiography of Maurice Wilkins. Oxford University Press. ISBN 978-0-198-60665-9.
The double helix is an important tertiary structure in nucleic acid molecules which is intimately connected with the molecule's secondary structure. A double helix is formed by regions of many consecutive base pairs. The nucleic acid double helix is a spiral polymer, usually right-handed, containing two nucleotide strands which base pair together.