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FISH is a technique that uses fluorescent probes to detect and localize specific DNA or RNA sequences on chromosomes or cells. Learn about the probes, preparation, hybridization, and visualization of FISH for various applications in biology and medicine.
Q-FISH uses labelled PNA probes to quantify telomeric sequences in chromosomal DNA using fluorescent microscopy and analysis software. It is used to study telomere length distribution and its association with various diseases, and can be combined with other FISH methods for more information.
TR-FRET is a technique that combines time-resolved fluorometry and Förster resonance energy transfer to measure biomolecular interactions. It uses lanthanide metals as donors and fluorescent dyes as acceptors, and has advantages over other screening methods.
A new study examined dogs that had been "trained" with soundboard buttons, and the findings are fascinating. A study published in PLOS ONE on August 28, 2024, highlights some interesting findings ...
An assay is a laboratory procedure to measure or test the presence, amount, or activity of a target entity. Learn about the etymology, general steps, and applications of assays in various fields such as medicine, mining, and biology.
The terms animal testing, animal experimentation, animal research, in vivo testing, and vivisection have similar denotations but different connotations.Literally, "vivisection" means "live sectioning" of an animal, and historically referred only to experiments that involved the dissection of live animals.
BCA assay is a biochemical assay for determining the total concentration of protein in a solution by measuring the color change of a purple-colored complex. The assay relies on two reactions: reduction of Cu2+ ions by peptide bonds and chelation of Cu1+ ions by bicinchoninic acid.
Some dog food products differentiate themselves as grain- or carbohydrate-free to offer the consumer an alternative, claiming carbohydrates in pet foods to be fillers with little or no nutritional value. A study published in Nature suggests that domestic dogs' ability to easily metabolize carbohydrates may be a key difference between wolves and ...
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