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The first description of cooperative binding to a multi-site protein was developed by A.V. Hill. [4] Drawing on observations of oxygen binding to hemoglobin and the idea that cooperativity arose from the aggregation of hemoglobin molecules, each one binding one oxygen molecule, Hill suggested a phenomenological equation that has since been named after him:
One manifestation of this is enzymes or receptors that have multiple binding sites where the affinity of the binding sites for a ligand is apparently increased, positive cooperativity, or decreased, negative cooperativity, upon the binding of a ligand to a binding site. For example, when an oxygen atom binds to one of hemoglobin's four binding ...
David Johnson, Deutsch's student in the study of social psychology, with his brother Roger Johnson, a science educator, and their sister, educator Edye Johnson Holubec, further developed positive interdependence theory as part of their research and work in teacher and professional training at the Cooperative Learning Center at the University of Minnesota (founded in 1969).
Positively cooperative binding: Once one ligand molecule is bound to the enzyme, its affinity for other ligand molecules increases. For example, the Hill coefficient of oxygen binding to haemoglobin (an example of positive cooperativity) falls within the range of 1.7–3.2. [5] <.
The positive reciprocity norm is a common social expectation in which a person who helps another person can expect positive feedback whether in the form of a gift, a compliment, a loan, a job reference, etc. In social psychology, positive reciprocity refers to responding to a positive action with another positive action (rewarding kind actions).
For example, a study conducted on the link between cohesion and performance in a governmental social service department found a low positive association between these two variables, while a separate study on groups in a Danish military unit found a high negative association between these two variables.
The binding problem refers to the overall encoding of our brain circuits for the combination of decisions, actions, and perception. It is considered a "problem" because no complete model exists. The binding problem can be subdivided into the four areas of perception, neuroscience, cognitive science, and the philosophy of mind. It includes ...
In social psychology, superordinate goals are goals that are worth completing but require two or more social groups to cooperatively achieve. [1] The idea was proposed by social psychologist Muzafer Sherif in his experiments on intergroup relations, run in the 1940s and 1950s, as a way of reducing conflict between competing groups. [2]