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Prednisone is a prodrug and must be converted to prednisolone by the liver before it becomes active. [6] [7] Prednisolone then binds to glucocorticoid receptors, activating them and triggering changes in gene expression. [4] Prednisone was patented in 1954 and approved for medical use in the United States in 1955.
[10] Prednisolone was discovered and approved for medical use in 1955. [10] It is on the World Health Organization's List of Essential Medicines. [11] It is available as a generic drug. [6] In 2022, it was the 136th most commonly prescribed medication in the United States, with more than 4 million prescriptions. [12] [13]
List of steroidogenesis inhibitors – steroidogenesis inhibitors, or inhibitors of steroid biosynthesis and metabolism; As well as lists of steroid esters, including: List of androgen esters – androgen esters; List of estrogen esters – estrogen esters; List of progestogen esters – progestogen esters; List of corticosteroid esters ...
A variety of steroid medications, from anti-allergy nasal sprays (Nasonex, Flonase) to topical skin creams, to eye drops , to prednisone have been implicated in the development of central serous retinopathy (CSR). [6] [7] Corticosteroids have been widely used in treating people with traumatic brain injury. [8]
Steroid ring system. This is a list of corticosteroids (glucocorticoids and mineralocorticoids) ... Cloprednol = 6-chloro-11β,17α,21-trihydroxypregna-1,4,6-triene-3 ...
Methyltestosterone (Android 5, Android 10, Android 25, Metandren, Oreton, Oreton Methyl, Testred, Virilon) Oxymetholone (Anadrol-50) Oxandrolone (Anavar) (Note that while the above anabolic steroids remain available in at least one formulation, many of the above-listed brand names have been discontinued.)
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Methylprednisolone (Depo-Medrol, Medrol, Solu-Medrol) is a synthetic glucocorticoid, primarily prescribed for its anti-inflammatory and immunosuppressive effects. [4] [5] [6] It is either used at low doses for chronic illnesses or used concomitantly at high doses during acute flares.