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Metronidazole, sold under the brand name Flagyl among others, is an antibiotic and antiprotozoal medication. [11] It is used either alone or with other antibiotics to treat pelvic inflammatory disease, endocarditis, and bacterial vaginosis. [11] It is effective for dracunculiasis, giardiasis, trichomoniasis, and amebiasis. [11]
Metronidazole is an antibiotic with an off-label use in eradicating H. pylori for treating gastric ulceration. Resistance of metronidazole is above 15% worldwide. [ 32 ] It is likely to be resistant so is not the first line choice of treatment. [ 44 ]
Structures with names 4- and 5-nitroimidazole are equivalent from the perspective of drugs since these tautomers readily interconvert. Drugs of the 5-nitro variety include metronidazole, tinidazole, nimorazole, dimetridazole, pretomanid, ornidazole, megazol, and azanidazole. Drugs based on 2-nitroimidazoles include benznidazole and azomycin. [3]
Indications can impact the pricing of medications through Value-based Pricing, also known as indication specific pricing or indication value-based pricing. [ 15 ] [ 16 ] Since drugs can be used for different indications, this form of pricing would set different prices for each indication based on the value the drug offers for whatever it is ...
Metronidazole: Flagyl: Infections caused by anaerobic bacteria; also amoebiasis, trichomoniasis, giardiasis: Discolored urine, headache, metallic taste, nausea; alcohol is contraindicated: Produces toxic free radicals that disrupt DNA and proteins. This non-specific mechanism is responsible for its activity against a variety of bacteria ...
Structurally it actually methyl-metronidazole. Effectiveness in the treatment of dientamoebiasis has been reported. [3] It has also been tested against Atopobium vaginae. [4] In the United States, secnidazole is FDA-approved for the treatment of bacterial vaginosis and trichomoniasis in adult women. [2] [5] It was approved in the United States ...
China’s government on Sunday denounced the Trump administration’s imposition of a long-threatened 10% tariff on Chinese imports while leaving the door open for talks with the US that could ...
Antimicrobial spectrum is similar to that of metronidazole and is more well tolerated; [1]: 1368 however there are concerns of lower relative efficacy. [3] It was first introduced for treating trichomoniasis before being recognized for its broad anti-protozoan and anti-anaerobic-bacterial capacities.
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