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The normal range of cardiac index at rest is 2.6–4.2 L/min/m 2. The cardiac index is frequently measured and used in both intensive care medicine and cardiac intensive care. The CI is a useful marker of how well the heart is functioning as a pump by directly correlating the volume of blood pumped by the heart with an individual's body surface ...
Developed by Adolf Eugen Fick (1829–1901), the Fick principle has been applied to the measurement of cardiac output. Its underlying principles may also be applied in a variety of clinical situations. In Fick's original method, the "organ" was the entire human body and the marker substance was oxygen. The first published mention was in ...
Cardiac output (CO) is the product of the heart rate (HR), i.e. the number of heartbeats per minute (bpm), and the stroke volume (SV), which is the volume of blood pumped from the left ventricle per beat; thus giving the formula: [ 3] Values for cardiac output are usually denoted as L/min.
The Frank–Starling law is named after the two physiologists, Otto Frank and Ernest Henry Starling. However, neither Frank nor Starling was the first to describe the relationship between the end-diastolic volume and the regulation of cardiac output. [ 5] The first formulation of the law was theorized by the Italian physiologist Dario Maestrini ...
The Framingham Risk Score is a sex-specific algorithm used to estimate the 10-year cardiovascular risk of an individual. The Framingham Risk Score was first developed based on data obtained from the Framingham Heart Study, to estimate the 10-year risk of developing coronary heart disease. [ 1] In order to assess the 10-year cardiovascular ...
Cardiac physiology. Cardiac physiology or heart function is the study of healthy, unimpaired function of the heart: involving blood flow; myocardium structure; the electrical conduction system of the heart; the cardiac cycle and cardiac output and how these interact and depend on one another.
Ejection fraction. An ejection fraction ( EF) is the volumetric fraction (or portion of the total) of fluid (usually blood) ejected from a chamber (usually the heart) with each contraction (or heartbeat ). It can refer to the cardiac atrium, [ 1] ventricle, [ 2] gall bladder, [ 3] or leg veins, [ 4] although if unspecified it usually refers to ...
The cardiac index is a measure of cardiac output divided by the BSA, giving a better approximation of the effective cardiac output; Chemotherapy is often dosed according to the patient's BSA. Glucocorticoid dosing is also expressed in terms of BSA for calculating maintenance doses or to compare high dose use with maintenance requirement.