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Specialty. Ophthalmology. Internuclear ophthalmoplegia ( INO) is a disorder of conjugate lateral gaze in which the affected eye shows impairment of adduction. When an attempt is made to gaze contralaterally (relative to the affected eye), the affected eye adducts minimally, if at all. The contralateral eye abducts, however with nystagmus.
Neuromyelitis optica spectrum disorder. Myasthenia Gravis. The one and a half syndrome is a rare weakness in eye movement affecting both eyes, in which one cannot move laterally at all, and the other can move only in outward direction. More formally, it is characterized by " a conjugate horizontal gaze palsy in one direction and an internuclear ...
Parinaud's syndrome is a constellation of neurological signs indicating injury to the dorsal midbrain. More specifically, compression of the vertical gaze center at the rostral interstitial nucleus of medial longitudinal fasciculus (riMLF). It is a group of abnormalities of eye movement and pupil dysfunction and is named for Henri Parinaud [ 6 ...
Chronic progressive external ophthalmoplegia ( CPEO) is a type of eye disorder characterized by slowly progressive inability to move the eyes and eyebrows. [ 1] It is often the only feature of mitochondrial disease, in which case the term CPEO may be given as the diagnosis. In other people suffering from mitochondrial disease, CPEO occurs as ...
Graves' ophthalmopathy, also known as thyroid eye disease ( TED ), is an autoimmune inflammatory disorder of the orbit and periorbital tissues, characterized by upper eyelid retraction, lid lag, swelling, redness ( erythema ), conjunctivitis, and bulging eyes ( exophthalmos ). [ 1] It occurs most commonly in individuals with Graves' disease ...
Parinaud's oculoglandular syndrome. Parinaud's oculoglandular syndrome (POS) is a medical condition characterized by a specific set of symptoms affecting the eye and nearby lymph nodes. Named after the French ophthalmologist Henri Parinaud, it should not be confused with the neurological syndrome caused by a lesion in the midbrain which is also ...
Kearns–Sayre syndrome ( KSS), oculocraniosomatic disorder or oculocranionsomatic neuromuscular disorder with ragged red fibers is a mitochondrial myopathy with a typical onset before 20 years of age. KSS is a more severe syndromic variant of chronic progressive external ophthalmoplegia (abbreviated CPEO), a syndrome that is characterized by ...
Horizontal gaze involves synchronous activation of the abducens muscle of one eye and the medial rectus muscle of the other, via communication through the Medial longitudinal fasciculus. Horizontal gaze palsies can be caused by a lesion affecting any structure in these pathways. Lesions to abducens nucleus or PPRF typically create an ...