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Valsartan/hydrochlorothiazide, sold under the brand name Diovan HCT among others, is a medication used to treat high blood pressure when valsartan is not sufficient. [6] It is a combination of valsartan, an angiotensin receptor blocker with hydrochlorothiazide , a diuretic . [ 7 ]
In March 2019, the FDA approved an additional generic version of valsartan to address the issue. [64] According to the agency, the shortage of valsartan was resolved in April 2020, [65] but the availability of the generic form remained unstable into July 2020. Pharmacies in the European Union were notified that the supply of the drug ...
Sacubitril/valsartan, sold under the brand name Entresto among others, is a fixed-dose combination medication for use in heart failure.It consists of the neprilysin inhibitor sacubitril and the angiotensin receptor blocker valsartan.
Hypertension is one of the major causes of chronic heart failure, a disease affecting more than 5 million Americans. As a result, hypertension drugs are widely used to reduce blood pressure in ...
Hydrochlorothiazide, sold under the brand name Hydrodiuril among others, is a diuretic medication used to treat hypertension and swelling due to fluid build-up. [4] Other uses include treating diabetes insipidus and renal tubular acidosis and to decrease the risk of kidney stones in those with a high calcium level in the urine. [4]
For each medicine surveyed, the local price is compared with an international reference price. This is usually drawn from MSH's International Medical Products Price Guide. This guide contains, for each drug, a set of prices from suppliers to developing countries and also a set of prices agreed by buyers such as government departments of health.
[7] [11] It is available as a generic medication. [7] In 2022, it was the third most commonly prescribed medication in the United States, with more than 82 million prescriptions. [ 12 ] [ 13 ] It is available in combination with amlodipine (as lisinopril/amlodipine ) and in combination with hydrochlorothiazide (as lisinopril/hydrochlorothiazide ).
In a four-year randomized controlled trial, candesartan was compared to placebo to see whether it could prevent or postpone the development of full-blown hypertension in people with so-called prehypertension. During the first two years of the trial, half of participants were given candesartan while the other half received placebo; candesartan ...