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Finasteride—which is also approved to treat enlarged prostate symptoms under the name Proscar—can be used alone or in combination with other hair loss treatments, like platelet-rich plasma ...
After using finasteride at a 5mg daily dose for one year, men reported the following side effects: ED (reported by 8.1 percent of men) Decreased libido (reported by 6.4 percent of men)
Reports of long-term, post-discontinuation adverse effects in some fraction of former finasteride users have led to a proposed post-finasteride syndrome (PFS), although some within the medical community question whether there is enough evidence to support a causal relationship between finasteride usage and PFS. [16]
Participants ranged from 18 to 83 years old and were taking 5-alpha-reductase inhibitors like finasteride and dutasteride, which is also used to treat prostate enlargement.
A 2017 population-based, matched-cohort study of 93,197 men aged 66 years and older with BPH found that finasteride and dutasteride were associated with a significantly increased risk of depression (HR Tooltip Hazard ratio, 1.94; 95% CI Tooltip Confidence interval, 1.73–2.16) and self-harm (HR, 1.88; 95% CI, 1.34–2.64) during the first 18 ...
Medical reviews suggest that LLLT is as effective or potentially more than other non invasive and traditional therapies like minoxidil and finasteride but further studies such as RCTs, long term follow up studies, and larger double blinded trials need to be conducted to confirm the initial findings. [46] [11] [47]
Originally developed to treat an enlarged prostate, finasteride, also known by the brand name Propecia, has been approved by the Food and Drug Administration for hair loss for nearly 30 years.
Dutasteride (Avodart) was the second steroidal 5α-reductase approved after finasteride. It is a competitive inhibitor of all three 5α-reductase isoenzymes [4] and it inhibits types 1 and 2 better than finasteride, leading to it causing further reduction in DHT, with >90% reduced DHT levels following 1 year of oral administration. [1]
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