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  2. Chromosomal translocation - Wikipedia

    en.wikipedia.org/wiki/Chromosomal_translocation

    The information in the second set of parentheses, when given, gives the precise location within the chromosome for chromosomes A and B respectively—with p indicating the short arm of the chromosome, q indicating the long arm, and the numbers after p or q refers to regions, bands and sub-bands seen when staining the chromosome with a staining ...

  3. Transcriptional regulation - Wikipedia

    en.wikipedia.org/wiki/Transcriptional_regulation

    A large part of gene regulation occurs through transcription factors that either recruit or inhibit the binding of the general transcription machinery and/or the polymerase. This can be accomplished through close interactions with core promoter elements, or through the long distance enhancer elements.

  4. Translation (biology) - Wikipedia

    en.wikipedia.org/wiki/Translation_(biology)

    The transcription-translation process description, mentioning only the most basic "elementary" processes, consists of: production of mRNA molecules (including splicing), initiation of these molecules with help of initiation factors (e.g., the initiation can include the circularization step though it is not universally required),

  5. Transcription (biology) - Wikipedia

    en.wikipedia.org/wiki/Transcription_(biology)

    Transcription is the process of copying a segment of DNA into RNA for the purpose of gene expression.Some segments of DNA are transcribed into RNA molecules that can encode proteins, called messenger RNA (mRNA).

  6. Eukaryotic chromosome fine structure - Wikipedia

    en.wikipedia.org/wiki/Eukaryotic_chromosome_fine...

    The poly-A tail is used in the initiation of translation and also seems to have an effect on the long-term stability (aging) of the mRNA. An unnamed region after the poly-A tail, but before the actual site for transcription termination, is spliced off during transcription, and so does not become part of the 3' UTR. Its function, if any, is unknown.

  7. Termination signal - Wikipedia

    en.wikipedia.org/wiki/Termination_signal

    Overview of transcription process. Termination of transcription occurs due to termination signal. In molecular biology, a termination signal is a sequence that signals the end of transcription or translation. [1] Termination signals are found at the end of the part of the chromosome being transcribed during transcription of mRNA.

  8. Eukaryotic transcription - Wikipedia

    en.wikipedia.org/wiki/Eukaryotic_transcription

    A eukaryotic cell has a nucleus that separates the processes of transcription and translation. Eukaryotic transcription occurs within the nucleus where DNA is packaged into nucleosomes and higher order chromatin structures. The complexity of the eukaryotic genome necessitates a great variety and complexity of gene expression control. Eukaryotic ...

  9. Transcription-translation coupling - Wikipedia

    en.wikipedia.org/wiki/Transcription-translation...

    Translation promotes transcription elongation and regulates transcription termination. Functional coupling between transcription and translation is caused by direct physical interactions between the ribosome and RNA polymerase ("expressome complex"), ribosome-dependent changes to nascent mRNA secondary structure which affect RNA polymerase activity (e.g. "attenuation"), and ribosome-dependent ...