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  2. Apoquel for Cats: Uses, Dosage, & Side Effects - AOL

    www.aol.com/lifestyle/apoquel-cats-uses-dosage...

    However, since its introduction to the market in 2013, the drug’s efficacy in cats has been subject to extensive study. The post Apoquel for Cats: Uses, Dosage, & Side Effects appeared first on ...

  3. Pregabalin - Wikipedia

    en.wikipedia.org/wiki/Pregabalin

    Pregabalin was found to possess 6-fold higher affinity than gabapentin for α 2 δ subunit-containing VGCCs in one study. [101] [102] However, another study found that pregabalin and gabapentin had similar affinities for the human recombinant α 2 δ-1 subunit (K i =32 nM and 40 nM, respectively). [103]

  4. Gabapentin - Wikipedia

    en.wikipedia.org/wiki/Gabapentin

    Gabapentin is recommended for use in focal seizures and neuropathic pain. [7] [10] Gabapentin is prescribed off-label in the US and the UK, [22] [23] for example, for the treatment of non-neuropathic pain, [22] anxiety disorders, sleep problems and bipolar disorder. [24]

  5. Gabapentinoid - Wikipedia

    en.wikipedia.org/wiki/Gabapentinoid

    Unlike gabapentin, which is transported solely by the LAT1, [22] [24] pregabalin seems to be transported not only by the LAT1 but also by other carriers. [1] The LAT1 is easily saturable, so the pharmacokinetics of gabapentin are dose-dependent, with diminished bioavailability and delayed peak levels at higher doses. [1]

  6. Calcium channel blocker - Wikipedia

    en.wikipedia.org/wiki/Calcium_channel_blocker

    Gabapentinoids, such as gabapentin and pregabalin, bind selectively to the α 2 δ protein that was first described as an integral part of voltage-gated calcium channels. These drugs do not directly block calcium channels [ 13 ] [ 14 ] but can alter the transport of functional calcium channels to the cell membrane and they also reduce the ...

  7. List of psychotropic medications - Wikipedia

    en.wikipedia.org/wiki/List_of_psychotropic...

    Celexa – an antidepressant of the SSRI class; Centrax – an anti-anxiety agent; Clozaril – atypical antipsychotic used to treat resistant schizophrenia; Concerta (methylphenidate) – an extended release form of methylphenidate

  8. Feline hyperesthesia syndrome - Wikipedia

    en.wikipedia.org/wiki/Feline_hyperesthesia_syndrome

    Around 9–12 months, or when the cat reaches maturity. Duration: The syndrome will remain present for the cat's entire life, but episodes only last for one to two minutes. Treatment: Behavioural adaptation, pharmaceuticals and alternative medicine. Prognosis: Good, provided the cat doesn't self-mutilate excessively.

  9. Gabapentin enacarbil - Wikipedia

    en.wikipedia.org/wiki/Gabapentin_enacarbil

    Gabapentin enacarbil (Horizant (ER) (U.S. Tooltip United States), Regnite (in Japan)) is an anticonvulsant and analgesic drug of the gabapentinoid class, and a prodrug to gabapentin. [1] It was designed for increased oral bioavailability over gabapentin, [ 2 ] [ 3 ] and human trials showed it to produce extended release of gabapentin with ...

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