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Interferon regulatory factors (IRF) are proteins which regulate transcription of interferons (see regulation of gene expression). [1] Interferon regulatory factors contain a conserved N-terminal region of about 120 amino acids, which folds into a structure that binds specifically to the IRF-element (IRF-E) motifs, which is located upstream of the interferon genes. [2]
IRF5 is a member of the interferon regulatory factor (IRF) family, a group of transcription factors with diverse roles, including virus-mediated activation of interferon, and modulation of cell growth, differentiation, apoptosis, and immune system activity.
The firm has been the subject of at least one lawsuit by financial regulators. The Commodity Futures Trading Commission, or CFTC, sued Wilson in November 2013 for alleged market manipulation in interest-rate swap futures during 2010 and 2011. [4] The case was dismissed in December 2018 after the court found no evidence of market manipulation by ...
The area is primarily composed of the ZIP codes 77085, 77045, and 77047. The ZIP code 77085, which covers an area similar to a triangle, roughly bounded by U.S. Route 90A (South Main), Hiram Clarke Road, and Beltway 8 (Sam Houston Tollway), saw the number of population rise to over 200% of its original population, between 2000 and 2010.
Interferon regulatory factor 8 (IRF8) also known as interferon consensus sequence-binding protein (ICSBP), is a protein that in humans is encoded by the IRF8 gene. [5] [6] [7] IRF8 is a transcription factor that plays critical roles in the regulation of lineage commitment and in myeloid cell maturation including the decision for a common myeloid progenitor (CMP) to differentiate into a ...
Fortune 500 companies based in Houston [1] Rank Company name 12: ExxonMobil: 48: Phillips 66: 60: Sysco: 105: Enterprise Products Partners: 106: Hewlett Packard ...
IRF3 is a member of the interferon regulatory transcription factor (IRF) family. [5] IRF3 was originally discovered as a homolog of IRF1 and IRF2.IRF3 has been further characterized and shown to contain several functional domains including a nuclear export signal, a DNA-binding domain, a C-terminal IRF association domain and several regulatory phosphorylation sites. [6]
International Rectifier was an American power management technology company manufacturing analog and mixed-signal ICs, advanced circuit devices, integrated power systems, and high-performance integrated components for computing.