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Pure choriocarcinoma of the testis represents the most aggressive pathologic variant of germ cell tumors in adults, characteristically with early hematogenous and lymphatic metastatic spread. Because of early spread and inherent resistance to anticancer drugs, patients have poor prognosis.
Bacteria involved in causing and treating cancers. This is a list of bacteria that have been identified as promoting or causing: . Uncontrolled growth of tissue in the body ...
Bacteria involved in causing and treating cancers. Cancer bacteria are bacteria infectious organisms that are known or suspected to cause cancer. [1] While cancer-associated bacteria have long been considered to be opportunistic (i.e., infecting healthy tissues after cancer has already established itself), there is some evidence that bacteria may be directly carcinogenic.
This glossary of biology terms is a list of definitions of fundamental terms and concepts used in biology, the study of life and of living organisms.It is intended as introductory material for novices; for more specific and technical definitions from sub-disciplines and related fields, see Glossary of cell biology, Glossary of genetics, Glossary of evolutionary biology, Glossary of ecology ...
CpG motifs are considered pathogen-associated molecular patterns due to their abundance in microbial genomes but their rarity in vertebrate genomes. [2] The CpG PAMP is recognized by the pattern recognition receptor ( PRR ) Toll-Like Receptor 9 ( TLR9 ), which is constitutively expressed only in B cells and plasmacytoid dendritic cells (pDCs ...
Sometimes it may develop into an invasive mole, or, more rarely into a choriocarcinoma. A choriocarcinoma is likely to spread quickly, [2] [3] but is very sensitive to chemotherapy, and has a very good prognosis. Trophoblasts are of particular interest to cell biologists because, like cancer, they can invade tissue (the uterus), but unlike ...
The macrophages also release ROS and RNOS. Levels of 8-oxo-2'-deoxyguanosine (8-OHdG), one of the predominant forms of free radical-induced oxidative DNA damages, [46] are increased more than 8-fold in DNA after infection by H. pylori, especially if the H. pylori are cagA positive. [47] The increase in 8-OHdG likely increases mutation. [48]
A human pathogen is a pathogen (microbe or microorganism such as a virus, bacterium, prion, or fungus) that causes disease in humans. The human physiological defense against common pathogens (such as Pneumocystis ) is mainly the responsibility of the immune system with help by some of the body's normal microbiota .