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Umbilical granuloma is the most common umbilical abnormality in newborn children or neonates, causing inflammation and drainage. [ 1 ] [ 2 ] [ 3 ] It may appear in the first few weeks of newborn infants during the healing process of the umbilical cord due to an umbilical mass. [ 4 ]
A periumbilical mass is not always a Sister Mary Joseph nodule. Other conditions that can cause a palpable periumbilical mass include umbilical hernia, infection, and endometriosis. Medical imaging, such as abdominal ultrasound, may be used to distinguish a Sister Mary Joseph nodule from another kind of mass. [2]
Cord blood is composed of all the elements found in whole blood – red blood cells, white blood cells, plasma, platelets. [6] Compared to whole blood some differences in the blood composition exist, for example, cord blood contains higher numbers of natural killer cells, lower absolute number of T-cells and a higher proportion of immature T-cells. [7]
Percutaneous umbilical cord blood sampling (PUBS), also called cordocentesis, fetal blood sampling, or umbilical vein sampling is a diagnostic genetic test that examines blood from the fetal umbilical cord to detect fetal abnormalities. [1] Fetal and maternal blood supply are typically connected in utero with one vein and two arteries to the fetus.
There are three types of umbilical prolapse that can occur: [12] overt umbilical cord prolapse: descent of the umbilical cord past the presenting fetal part. In this case, the cord is through the cervix and into or beyond the vagina. Overt umbilical cord prolapse requires rupture of membranes. This is the most common type of cord prolapse.
An umbilical hernia is a health condition where the abdominal wall behind the navel is damaged. It may cause the navel to bulge outwards—the bulge consisting of abdominal fat from the greater omentum or occasionally parts of the small intestine. The bulge can often be pressed back through the hole in the abdominal wall, and may "pop out" when ...
Nuchal cord, when the umbilical cord is (tightly) around the neck of the fetus [2] Entanglement of the cord [2] Knot in the cord [2] Cord prolapse, where the umbilical cord exits the birth canal before the baby, which can cause cord compression. [3] As a complication of oligohydramnios in which there is insufficient amniotic fluid
Human umbilical vein endothelial cells pictured down a microscope at 200x zoom. Human umbilical vein endothelial cells (HUVECs) are cells derived from the endothelium of veins from the umbilical cord. They are used as a laboratory model system for the study of the function and pathology of endothelial cells (e.g., angiogenesis). [1]