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Lung transplantation is the therapeutic measure of last resort for patients with end-stage lung disease who have exhausted all other available treatments without improvement. A variety of conditions may make such surgery necessary. As of 2005, the most common reasons for lung transplantation in the United States were: [2]
A lung from a 16-year-old donor would first be offered to the person in the age group 12–17 with the highest lung allocation score and matching blood type in the vicinity of the transplant center. If there no suitable recipient in that age group, it would next be offered to the highest LAS-scoring candidate who is under 12 years of age.
In 1984, he performed the world’s first successful paediatric heart transplant. [30] 1994–1995: John Wallwork: Wallwork performed the world's first heart-lung and liver transplant with Sir Roy Calne in 1986. [31] 1995–1996: Sharon Hunt: Pioneered work on post-operative care of heart transplant patients. [32] 1996–1997: William Baumgartner
Ex vivo lung perfusion, EVLP, is a form of machine perfusion aimed at sustaining the active aerobic cellular metabolism of donor lungs outside the donor's body prior to lung transplantation. This medical preservation technique typically occurs within a specialised machine engineered to mimic the conditions of the natural circulatory system .
The Journal of Heart and Lung Transplantation is a monthly peer-reviewed medical journal covering heart and lung transplantation. It was established in 1981 as Heart Transplantation, and was renamed to the Journal of Heart Transplantation in 1984. It obtained its current name in 1991.
Most recently in 2022, the WHO guidelines were updated by the European Society of Cardiology (ESC) and European Respiratory Society (ERS). [4] These guidelines are endorsed by the International Society for Heart and Lung Transplantation, and provide the current framework for understanding and treatment of pulmonary hypertension. [4]
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The Journal of Heart and Lung Transplantation published updated guidelines in 2001 for grading the severity of BOS. [20] The original guidelines and classification system were published in 1993 by the International Society for Heart and Lung Transplantation. [20] Their scoring system is based on the changes in FEV 1 in patients from their ...