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The "O" in the name stands for oxygen-labile; the other related toxin being oxygen-stable streptolysin-S. The main function of streptolysin O is to cause hemolysis (the breaking open of red blood cells)—in particular, beta-hemolysis. Increased levels of ASO titre in the blood could cause damage to the heart and joints.
Bacterial culture may need to be performed in cases of a negative rapid streptococcal test. [33] An increase in antistreptolysin O streptococcal antibody titer following the acute infection can provide retrospective evidence of GABHS infection and is considered definitive proof of GABHS infection, but not necessarily of the tonsils. [34]
This may include a full blood count (FBC), erythrocyte sedimentation rate (ESR), antistreptolysin-O (ASO) titer and throat culture, urinalysis, intradermal tuberculin test, and a chest x-ray. [22] The ESR is typically high, the C-reactive protein elevated, and the blood showing an increase in white blood cells.
Streptolysin O An exotoxin, one of the bases of the organism's beta-hemolytic property, streptolysin O causes an immune response and detection of antibodies to it; antistreptolysin O (ASO) can be clinically used to confirm a recent infection. It is damaged by oxygen.
In a patient with suspected post-streptococcal glomerulonephritis, anti-streptolysin-O titres (ASOTs) can be negative even after strep pharyngitis. Some studies suggest that up to 85% of patients with acute rheumatic fever from group A strep infection will be positive for ASO titers, leaving 15% of patients having been diagnosed with rheumatic ...
Egyptian and Qatari mediators were working to salvage the ceasefire deal between Israel and Hamas on Wednesday, according to Egypt’s state-run Al-Qahera News TV, which is close to the country's ...
What Makes Pam-Cakes Special? Simple Ingredients: There’s nothing fancy or unexpected about this recipe.You’ll find all the expected ingredients: flour, eggs, buttermilk, baking powder and ...
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