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  2. Bone marrow failure - Wikipedia

    en.wikipedia.org/wiki/Bone_marrow_failure

    Myelodysplastic syndrome (MDS) is a form of blood cancer in which the bone marrow no longer produces enough healthy, normal blood cells. [9] MDS are a frequently unrecognized and rare group of bone marrow failure disorders, yet the incidence rate has rose from 143 reported cases in 1973 to approximately 15,000 cases in the United States each year.

  3. Aplastic anemia - Wikipedia

    en.wikipedia.org/wiki/Aplastic_anemia

    Aplastic anemia [2] (AA) [3] is a severe hematologic condition in which the body fails to make blood cells in sufficient numbers. Blood cells are produced in the bone marrow by stem cells that reside there. [4] Aplastic anemia causes a deficiency of all blood cell types: red blood cells, white blood cells, and platelets. [5] [6]

  4. Pure red cell aplasia - Wikipedia

    en.wikipedia.org/wiki/Pure_red_cell_aplasia

    Pure red cell aplasia (PRCA) or erythroblastopenia refers to a type of aplastic anemia affecting the precursors to red blood cells but usually not to white blood cells. In PRCA, the bone marrow ceases to produce red blood cells. There are multiple etiologies that can cause PRCA.

  5. Cytopenia - Wikipedia

    en.wikipedia.org/wiki/Cytopenia

    Pancytopenia – when all three types of blood cells; red blood cells, white blood cells, and platelets, are all deficient. This is a life-threatening disorder that is a characteristic of aplastic anemia. [3] There are also two general causes of cytopenia: autoimmune and refractory.

  6. List of hematologic conditions - Wikipedia

    en.wikipedia.org/wiki/List_of_hematologic_conditions

    Anemia of prematurity is a form of anemia affecting preterm infants [25] with decreased hematocrit. [26] Aplastic anemia: D60-D61: 866: Aplastic anemia is a condition where bone marrow does not produce sufficient new cells to replenish blood cells. [27] Autoimmune hemolytic anemia: D59.0-D59.1

  7. Reticulocyte production index - Wikipedia

    en.wikipedia.org/wiki/Reticulocyte_production_index

    RI < 0.5% with anemia indicates maturation disorder, meaning loss of red blood cells, but also decreased production of reticulocytes (i.e., an inadequate response to correct the anemia) and therefore red blood cells. [2] RI > 2.5% with anemia indicates loss of red blood cells (from causes such as destruction, bleeding, etc.), with an increased ...

  8. Aplasia - Wikipedia

    en.wikipedia.org/wiki/Aplasia

    Aplastic anemia patients present with symptoms related to a decrease in hematopoietic cell production in the bone marrow. The onset is gradual, and the first symptom is frequently anemia or bleeding, though a high temperature or infections may be present at the onset. The following are examples of specific manifestations: [12]

  9. Hematologic disease - Wikipedia

    en.wikipedia.org/wiki/Hematologic_disease

    Paroxysmal nocturnal hemoglobinuria (rare acquired clonal disorder of red blood cell surface proteins) Direct physical damage to RBCs Microangiopathic hemolytic anemia; Secondary to artificial heart valve(s) Aplastic anemia. Fanconi anemia; Diamond–Blackfan anemia (inherited pure red cell aplasia) Acquired pure red cell aplasia; Decreased ...

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