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Dermatomyositis (DM) is a long-term inflammatory autoimmune disorder which affects the skin and the muscles. Its symptoms are generally a skin rash and worsening ...
Multifocal motor neuropathy (MMN) is a progressively worsening condition where muscles in the extremities gradually weaken.The disorder, a pure motor neuropathy syndrome, is sometimes mistaken for amyotrophic lateral sclerosis (ALS) because of the similarity in the clinical picture, especially if muscle fasciculations are present.
Mixed connective tissue disease, systemic lupus erythematosus, polymyositis, dermatomyositis [1] Treatment: Supportive care [1] Medication: Corticosteroids, methotrexate, non-steroidal anti-inflammatory drugs (NSAIDs) [2] Prognosis: Localized: Normal life expectancy [7] Systemic: Decreased life expectancy [3] Frequency: 3 per 100,000 per year ...
This usually subsides over time, however it may reappear during flares. Between 50% and 75% of people with MCTD will experience anemia, lymphopenia, or leukopenia. Anemia of chronic disease is the most common type of anemia seen in MCTD. [10] Thrombocytopenia can develop in MCTD but is less common than leukopenia or anemia. [18] [43]
Around 3.2 children per million per year are diagnosed with DM (termed juvenile dermatomyositis), with an average age of onset of seven years. Diagnosis of adult DM commonly occurs between 30 and 50 years of age. PM is an adult disease, usually emerging after the age of twenty.
Dermatomyositis-like rashes are seen in 32–44% of those with antisynthetase syndrome. This includes heliotropic rash, Gottron papules, and lesions of the psoriasiform type that span the hand's dorsum and resemble the morphology of mechanics hands. [26]
[11] sIBM does not significantly affect life expectancy, [1] although death related to malnutrition and respiratory failure can occur. [12] The risk of serious injury due to falls is increased. [1] There is no effective treatment for the disease as of 2019. [1]
Juvenile dermatomyositis (JDM) is an idiopathic inflammatory myopathy (IMM) of presumed autoimmune dysfunction resulting in muscle weakness among other complications. It manifests itself in children; it is the pediatric counterpart of dermatomyositis .