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Choriocarcinoma is a malignant, trophoblastic [1] cancer, usually of the placenta. It is characterized by early hematogenous spread to the lungs. It belongs to the malignant end of the spectrum in gestational trophoblastic disease (GTD). It is also classified as a germ cell tumor and may arise in the testis or ovary.
The 1997 International Germ Cell Consensus Classification [17] is a tool for estimating the risk of relapse after treatment of malignant germ-cell tumor. A small study of ovarian tumors in girls [ 18 ] reports a correlation between cystic and benign tumors, and conversely, solid and malignant tumors.
The diagnosis of a mediastinal germ cell tumor should be considered in all young males with a mediastinal mass. In addition to physical examination and routine laboratory studies, initial evaluation should include CT of the chest and abdomen, and determination of serum levels of HCG and alpha-fetoprotein.
Dysgerminoma is the most common type of malignant germ-cell ovarian cancer. Dysgerminoma usually occurs in adolescence and early adult life; about 5% occur in prepubertal children. Dysgerminoma is extremely rare after age 50. It occurs in both ovaries in 10% of patients and, in a further 10%, a microscopic tumor is in the other ovary. [citation ...
In contrast, the epithelial cells originate from the outer epithelial lining surrounding the gonad while the germ cell tumors arise from the precursor cells of the gametes, hence the name germ cell. [1] In humans, this group accounts for 8% of ovarian cancers and under 5% of testicular cancers. Their diagnosis is histological: only a biopsy of ...
Shen’s cancer had spread to the pleura — which covers the lungs, chest cavity along the ribs, the sac around the heart, the nerves that control the diaphragm, the trachea, the windpipe, the ...
A mixed germ cell tumor in the testes. On the left side shows yolk sac tumor, and on the right side shows embryonal carcinoma. Under the classification of the biology GCT, there is a more detailed classification contains specific types of extracranial extragonadal germ cell tumor. There are two types, teratomas, and malignant GCTs.
A mediastinal tumor is a tumor in the mediastinum, the cavity that separates the lungs from the rest of the chest. It contains the heart , esophagus , trachea , thymus , and aorta . The most common mediastinal masses are thymoma (20% of mediastinal tumors), usually found in the anterior mediastinum, followed by neurogenic Timor (15–20% ...