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The between-systems memory interference model describes the inhibition of non-hippocampal systems of memory during concurrent hippocampal activity. Specifically, Fraser Sparks, Hugo Lehmann, and Robert Sutherland [ 65 ] found that when the hippocampus was inactive, non-hippocampal systems located elsewhere in the brain were found to consolidate ...
Damage to the hippocampus and surrounding area can cause anterograde amnesia, the inability to form new memories. [3] This implies that the hippocampus is important not only for storing cognitive maps, but for encoding memories.
According to Gilboa et al., patients with localized hippocampal damage can score well on a test if it is based on familiarity. [22] Poreh et al. [23] describe a case study of patient A.D., whose damage to the fornix rendered the hippocampus useless, but spared adjacent cortical areas – a fairly rare injury. When the patient was given a test ...
Alcohol acts as a general central nervous system depressant, but it also affects some specific areas of the brain to a greater extent than others. Memory impairment caused by alcohol has been linked to the disruption of hippocampal function—particularly affecting gamma-Aminobutyric acid (GABA) and N-methyl-D-aspartate (NMDA) neurotransmission which negatively impacts long-term potentiation ...
The hippocampus deals largely with memory consolidation, [35] where information from the working memory and short-term memory is encoded into long-term storage for future retrieval. Amnesic patients with damage to the hippocampus are able to demonstrate some degree of unimpaired semantic memory , despite a loss of episodic memory , due to ...
The hippocampus is responsible for encoding new memory. Episodic memory is more likely to be affected than semantic memory. The damage is usually caused by head trauma, cerebrovascular accident, stroke, tumor, hypoxia, encephalitis, or chronic alcoholism. People with retrograde amnesia are more likely to remember general knowledge rather than ...
The difference in memory between normal aging and a memory disorder is the amount of beta-amyloid deposits, hippocampal neurofibrillary tangles, or amyloid plaques in the cortex. If there is an increased amount, memory connections become blocked, memory functions decrease much more than what is normal for that age and a memory disorder is ...
The hippocampus and amygdala have been connected with transference of memory from short-term memory to long-term memory. [29] Thalamus and hypothalamus, located in the forebrain, are part of the limbic system ; they are responsible for regulating different hormones and emotional and physical reactions to situations, including emotional stress ...