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Cannabis plants, like many others, biochemically synthesize terpenes with intense aromas as a method of chemical defense in attempts to repel predators, and invite pollinators. Because terpenes and terpenoids are biologically active molecules, it is possible variations in terpenes may elicit different biological and psychoactive responses in ...
A dried cannabis flower. The short-term effects of cannabis are caused by many chemical compounds in the cannabis plant, including 113 [clarification needed] different cannabinoids, such as tetrahydrocannabinol (THC), and 120 terpenes, [1] which allow its drug to have various psychological and physiological effects on the human body.
Many terpenes have been shown to have pharmacological effects. Terpenes are also components of some ... is the active ingredient in marijuana. Physical and chemical ...
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The phrase entourage effect was introduced in 1999. [9] [10] While originally identified as a novel method of endocannabinoid regulation by which multiple endogenous chemical species display a cooperative effect in eliciting a cellular response, the term has evolved to describe the polypharmacy effects of combined cannabis phytochemicals or whole plant extracts. [11]
Both hops and cannabis contain terpenes and terpenoids; tetrahydrocannabinol (THC) is a terpenoid. [3] [4] Hops lack the enzyme that could convert cannabigerolic acid into THC or CBD, [5] but it could be inserted using genetic engineering as was done in 2019 for yeast. [6] [7]
CBN was the first cannabis compound to be isolated from cannabis extract in the late 1800s. Its structure and chemical synthesis were achieved by 1940 [34], followed by some of the first pre-clinical research studies to determine the effects of individual cannabis-derived compounds in vivo. [35]
Guaiol is one of many terpenes found in Cannabis and it has been associated with anxiolytic activity. [3] [4] Reactions