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The middle cerebellar peduncle is the largest of the three cerebellar peduncles. It connects the pons and cerebellum.It consists almost entirely of fibers passing from the pons to the cerebellum (fibrocerebellar fibers); the fibers arise from the pontine nuclei and decussate within the pons before entering the peduncle [1] to end in the contralateral cerebellar hemisphere.
The cerebellar peduncles are three paired bundles of fibres that connect the cerebellum to the brain stem. [1] Superior cerebellar peduncle is a paired structure of white matter that connects the cerebellum to the mid-brain. Middle cerebellar peduncles connect the cerebellum to the pons and are composed entirely of centripetal fibers.
The cerebral peduncles (In Latin, ped-means 'foot'.) are the two stalks that attach the cerebrum to the brainstem. [1] They are structures at the front of the midbrain which arise from the ventral pons and contain the large ascending (sensory) and descending (motor) tracts that run to and from the cerebrum from the pons.
The middle peduncle is the largest of the three and its afferent fibers are grouped into three separate fascicles taking their inputs to different parts of the cerebellum. The inferior cerebellar peduncle receives input from afferent fibers from the vestibular nuclei, spinal cord and the tegmentum.
The corticopontocerebellar pathway is the largest pathway associated with the cerebellum. Arising in the cerebral cortex these fibers first terminate ipsilaterally in the pontine nuclei. Then the fibers decussate and form the middle cerebellar peduncle, terminating in the cerebellar cortex as mossy fibers.
In medicine, a mass such as a cyst or polyp is said to be pedunculated if it is supported by a peduncle. [2] There are in total three types of peduncles in the cerebellum of the human brain, known as superior cerebellar peduncle, middle cerebellar peduncle, and inferior cerebellar peduncle. [3]
The cerebral peduncles each form a lobe ventrally of the tegmentum, on either side of the midline. Beyond the midbrain, between the lobes, is the interpeduncular fossa , which is a cistern filled with cerebrospinal fluid [ citation needed ] .
Pontocerebellar fibers are the sole efferent pathway of the pontine nuclei. The fibers mostly decussate within the pons to pass through the (contralateral) middle cerebellar peduncle to terminate in the contralateral cerebellum as mossy fibers; they form terminal synapses in the cerebellar cortex, but also issue collaterals to the cerebellar nuclei.