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  2. Ganoderma microsporum immunomodulatory protein - Wikipedia

    en.wikipedia.org/wiki/Ganoderma_microsporum_immu...

    However, the levels of GMI found in both the mycelium and fruiting body are very low. [citation needed] In 2005, researchers utilized genetic and bio-engineering methods to obtain purified GMI, and proved that the protein is structurally similar to LZ-8, the first fungal immunomodulatory protein discovered in 1989. The name GMI is derived from ...

  3. Hyperalgesia - Wikipedia

    en.wikipedia.org/wiki/Hyperalgesia

    Hyperalgesia (/ ˌ h aɪ p ər æ l ˈ dʒ iː z i ə / or /-s i ə /; hyper from Greek ὑπέρ (huper) 'over' + -algesia from Greek ἄλγος (algos) 'pain') is an abnormally increased sensitivity to pain, which may be caused by damage to nociceptors or peripheral nerves and can cause hypersensitivity to stimulus.

  4. Nonsteroidal anti-inflammatory drug - Wikipedia

    en.wikipedia.org/wiki/Nonsteroidal_anti...

    Pain following surgery can be significant, and many people require strong pain medications such as opioids. There is some low-certainty evidence that starting NSAID painkiller medications in adults early, before surgery, may help reduce post-operative pain, and also reduce the dose or quantity of opioid medications required after surgery. [ 29 ]

  5. GM1 gangliosidoses - Wikipedia

    en.wikipedia.org/wiki/GM1_gangliosidoses

    The GM1 gangliosidoses, usually shortened to GM1, are gangliosidoses caused by mutation in the GLB1 gene resulting in a deficiency of beta-galactosidase.The deficiency causes abnormal storage of acidic lipid materials in cells of the central and peripheral nervous systems, but particularly in the nerve cells, resulting in progressive neurodegeneration.

  6. Anti-inflammatory - Wikipedia

    en.wikipedia.org/wiki/Anti-inflammatory

    Nonsteroidal anti-inflammatory drugs (NSAIDs) alleviate pain by counteracting the cyclooxygenase (COX) enzyme. [1] On its own, COX enzyme synthesizes prostaglandins , creating inflammation. In whole, the NSAIDs prevent the prostaglandins from ever being synthesized, reducing or eliminating the inflammation and resulting pain.

  7. Pentazocine - Wikipedia

    en.wikipedia.org/wiki/Pentazocine

    Pentazocine, [3] sold under the brand name Talwin among others, is a painkiller used to treat moderate to severe pain. It is believed to work by activating (agonizing) κ-opioid receptors (KOR) and μ-opioid receptors (MOR). As such it is called an opioid as it delivers its effects

  8. Pain management - Wikipedia

    en.wikipedia.org/wiki/Pain_management

    Most physicians and other health professionals provide some pain control in the normal course of their practice, and for the more complex instances of pain, they also call on additional help from a specific medical specialty devoted to pain, which is called pain medicine. Pain management often uses a multidisciplinary approach for easing the ...

  9. Methoxyflurane - Wikipedia

    en.wikipedia.org/wiki/Methoxyflurane

    Methoxyflurane, sold under the brand name Penthrox among others, is an inhaled medication primarily used to reduce pain following trauma. [5] [6] It may also be used for short episodes of pain as a result of medical procedures. [4] Onset of pain relief is rapid and of a short duration. [4] Use is only recommended with direct medical supervision ...

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