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Chronic pain and neuropathic pain are indications for which there is high unmet need in the clinic. PEA has been tested in a variety of animal models for chronic and neuropathic pain, because cannabinoids, such as THC , have been proven to be effective in neuropathic pain states. [ 23 ]
Cannabis (/ ˈ k æ n ə b ɪ s /), [2] commonly known as marijuana (/ ˌ m æ r ə ˈ w ɑː n ə /), [3] weed, and pot, among other names, is a non-chemically uniform drug from the cannabis plant. Native to Central or South Asia, the cannabis plant has been used as a drug for both recreational and entheogenic purposes and in various ...
Where risks or harms is the reason for withdrawal, this will usually have been prompted by unexpected adverse effects that were not detected during Phase III clinical trials, i.e. they were only made apparent from postmarketing surveillance data collected from the wider community over longer periods of time.
The authors state that additional randomized controlled trials of different cannabis products are necessary to make conclusive recommendations. [18] When cannabis is inhaled to relieve pain, blood levels of cannabinoids rise faster than when oral products are used, peaking within three minutes and attaining an analgesic effect in seven minutes ...
Today, pharmaceutical companies try to make new drugs as selective as possible to minimise binding to antitargets and hence reduce the occurrence of side effects and risk of adverse reactions. Examples of compounds often cited as "dirty drugs" include tramadol , chlorpromazine , olanzapine , dextromethorphan , ibogaine , and ethanol , all of ...
Horny goat weed can also change hormone levels, so you shouldn't take it if you have a hormone-sensitive cancer. It may be unadvisable to take horny goat weed if you're on certain medications or ...
Female cannabis plants not only contain dronabinol but at least 113 other cannabinoids, [35] including cannabidiol (CBD), thought to be the major anticonvulsant that helps people with multiple sclerosis; [36] and cannabichromene (CBC), an anti-inflammatory which may contribute to the pain-killing effect of cannabis.
Traditional resin made from live cannabis plant. [21] Charlotte's Web: Industry trade name for cannabis sativa strain. [73] Cola English. Part of a cannabis plant. [21] [74] Colombian Traditional heirloom strain of cannabis. [21] Concentrate: English. Industry trade name for cannabis extract. [75] Critical Mass Industry trade name for cannabis ...