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Primary amines can be protected as benzophenone imines, and the protected amines are stable in flash chromatography. [7] Buchwald-Hartwig amination involves coupling aromatic halide and amine to form carbon-nitrogen bonds with the help of palladium-based catalysts. Benzophenone imine can be used as an ammonia-equivalent in such reactions. [1]
Benzophenone is a naturally occurring organic compound with the formula (C 6 H 5) 2 CO, generally abbreviated Ph 2 CO. Benzophenone has been found in some fungi, fruits and plants, including grapes. [4] It is a white solid with a low melting point and rose-like odor [5] that is soluble in organic solvents. Benzophenone is the simplest ...
Benzophenone imine, an organic compound with the formula of (C 6 H 5) 2 C=NH; 2-Aminofluorene, a synthetic arylamine This page was last edited on 28 February 2023, at ...
An experimental nasal spray has helped clear toxic protein buildups in the brains of mouse models of Alzheimer's. Its developers believe the spray may help delay Alzheimer's by at least a decade.
It is also prepared commercially by ketonization of benzoic acid and propionic acid over calcium acetate and alumina at 450–550 °C: [1] C 6 H 5 CO 2 H + CH 3 CH 2 CO 2 H → C 6 H 5 C(O)CH 2 CH 3 + CO 2 + H 2 O. Ludwig Claisen discovered that α-methoxystyrene forms this compound when heated for an hour at 300 °C (65% yield). [2] [3]
The FDA proposed a ban on phenylephrine, a common decongestant found in cold and cough medications. Here’s why and a list of medicines with phenylephrine.
Amidoximes are oximes of amides (R 1 C(=O)NR 2 R 3) with general structure R 1 C(=NOH)NR 2 R 3. Oximes are usually generated by the reaction of hydroxylamine with aldehydes (R−CH=O) or ketones (RR’C=O). The term oxime dates back to the 19th century, a combination of the words oxygen and imine. [1]
The 24-hour flu is usually a type of gastroenteritis, which is an inflammation of the intestines and stomach, says William Schaffner, M.D., an infectious disease specialist and professor at the ...
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