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  2. Spironolactone - Wikipedia

    en.wikipedia.org/wiki/Spironolactone

    Therefore, it is recommended that people using this medication avoid potassium supplements and salt substitutes containing potassium. [169] Physicians must be careful to monitor potassium levels in both males and females who are taking spironolactone as a diuretic, especially during the first twelve months of use and whenever the dosage is ...

  3. Hair Loss in Women: Everything You Need to Know - AOL

    www.aol.com/hair-loss-women-everything-know...

    Spironolactone is a once-a-day tablet that can stop hair loss from progressing and encourage new hair growth. It’s especially useful for women with hormonal issues like PCOS. It may take six to ...

  4. Does Low Estrogen Cause Hair Loss? - AOL

    www.aol.com/does-low-estrogen-cause-hair...

    Using certain types of medication. ... (0.25 to 2.5 mg daily). Spironolactone. ... Women who are pregnant or trying to get pregnant shouldn’t take spironolactone.

  5. Androgenetic Alopecia: Everything to Know About Male ... - AOL

    www.aol.com/androgenetic-alopecia-everything...

    In some cases, other medications like spironolactone may be prescribed off-label for hair loss. This is typically only used in women and not in men, because in men it can lead to gynecomastia ...

  6. Pharmacodynamics of spironolactone - Wikipedia

    en.wikipedia.org/wiki/Pharmacodynamics_of...

    [96] [85] 17β-HSD2 is a key enzyme responsible for inactivation of estradiol into estrone in various tissues, and inhibition of 17β-HSD2 by spironolactone may be involved in the gynecomastia and altered ratio of circulating testosterone to estradiol associated with the medication. [84] [99] Spironolactone has also been associated with ...

  7. Mineralocorticoid receptor antagonist - Wikipedia

    en.wikipedia.org/wiki/Mineralocorticoid_receptor...

    Eplerenone is a newer drug that was developed as a spironolactone analog with reduced adverse effects. In addition to the y-lactone ring and the substituent on C-7, eplerenone has a 9α,11α-epoxy group. This group is believed to be the reason why eplerenone has a 20-40-fold lower affinity for the mineralocorticoid receptor than spironolactone. [7]

  8. Could Spironolactone Help Women With Hair Thinning, Facial ...

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  9. Feminizing hormone therapy - Wikipedia

    en.wikipedia.org/wiki/Feminizing_hormone_therapy

    [105] [106] Hospitalization and/or death can potentially result from high potassium levels due to spironolactone, [105] [106] [107] but the risk of high potassium levels in people taking spironolactone appears to be minimal in those without risk factors for it. [100] [108] [109] As such, monitoring of potassium levels may not be necessary in ...

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