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Intestinal villi (sg.: villus) are small, finger-like projections that extend into the lumen of the small intestine.Each villus is approximately 0.5–1.6 mm in length (in humans), and has many microvilli projecting from the enterocytes of its epithelium which collectively form the striated or brush border.
Goblet cells secrete mucus, which lubricates the passage of food along and protects the intestinal wall from digestive enzymes. In the small intestine, villi are folds of the mucosa that increase the surface area of the intestine. The villi contain a lacteal, a vessel connected to the lymph system that aids in the removal of lipids and tissue ...
Illustration of the brush border membrane of small intestinal villi. A brush border (striated border or brush border membrane) is the microvillus-covered surface of simple cuboidal and simple columnar epithelium found in different parts of the body. Microvilli are approximately 100 nanometers in diameter and their length varies from ...
Microvillus inclusion disease, previously known as Davidson's disease, congenital microvillus atrophy and, less specifically, microvillus atrophy (note: microvillus is often misspelled as microvillous), is a rare genetic disorder of the small intestine that is inherited in an autosomal recessive pattern. [1] [2]
Refractory coeliac disease should not be confused with the persistence of symptoms despite gluten withdrawal [114] caused by transient conditions derived from the intestinal damage, [111] [112] [115] which generally revert or improve several months after starting a gluten-free diet, [116] [117] such as small intestinal bacterial overgrowth ...
Micrograph of the small intestine mucosa showing the intestinal villi and crypts of Lieberkühn. The three sections of the small intestine look similar to each other at a microscopic level, but there are some important differences. The parts of the intestine are as follows: This cross section diagram shows the 4 layers of the small intestine wall.
The combination of the circular folds, the villi, and the microvilli increases the absorptive area of the mucosa about 600-fold, making a total area of about 250 m 2 (2,700 sq ft) for the entire small intestine. [20]
The intestinal mucosa turnover is dynamic, nutrient-dependent and rapid, [52] and malnourished children have rate-limiting stores for repairing mucosal damage. [24] The nutrients known to contribute to intestinal regeneration and improved barrier function are sulphur containing amino acids, [53] glutamine, vitamin A and zinc.