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Cases of the sexually transmitted infection jumped a jaw-dropping 128% in women from 2019 to 2022, with a nine-fold increase in syphilis transmitted to babies during pregnancy.
A staggering 207,000 syphilis cases were reported in the US in 2022 — an 80% increase since 2018. Syphilis cases soar to highest level in 70 years — CDC sounds alarm over ‘unacceptable’ crisis
By the time people are over the age of 50, Park says “about 1 in 5 of us has herpes type 2,” which causes genital herpes. “And then when we talk about herpes type 1, which causes oral herpes ...
Rates of syphilis in 2000–2005 among low-risk groups such as women without children and unmarried people were about 0.3–0.6% while rates among high-risk groups such as drug users and MSM were about 7–15%. [11] Rates are greatest among men who have sex with men and sex workers. [10]
Neurosyphilis is the infection of the central nervous system by Treponema pallidum, the bacterium that causes the sexually transmitted infection syphilis.In the era of modern antibiotics, the majority of neurosyphilis cases have been reported in HIV-infected patients.
Intravenous penicillin has been the primary treatment for syphilitic aortitis since the 1940s. The underlying bacterium of syphilis, T. pallidum, continues to be sensitive to penicillin as the lack of horizontal gene transfer mechanisms makes it difficult for the bacterium to mutate and resist treatment. [4]
Penicillin quickly became an effective and cost-effective treatment, and after the highest number of cases in the U.S. were recorded in 1943, cases declined over the next 80 years, CDC data shows.
Both Jarisch and Herxheimer observed reactions in patients with syphilis treated with mercury. The reaction was first seen following treatment in early and later stages of syphilis treated with Salvarsan, mercury, or antibiotics. Jarisch thought that the reaction was caused by a toxin released from the dying spirochetes. [11]