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Some antibiotics are actively eliminated through the kidneys. Impaired renal function will require reduction of the drug dose to avoid excessively elevated plasma drug concentrations that could lead to toxicity. [17] Dose adjustment can be done by reducing the amount administered in each dose or by increasing the interval between doses. [17]
Doxycycline was patented in 1957 and came into commercial use in 1967. [7] [8] It is on the World Health Organization's List of Essential Medicines. [9] Doxycycline is available as a generic medicine. [1] [10] In 2022, it was the 68th most commonly prescribed medication in the United States, with more than 9 million prescriptions. [11] [12]
Tetracyclines are generally used in the treatment of infections of the urinary tract, respiratory tract, and the intestines and are also used in the treatment of chlamydia, especially in patients allergic to β-lactams and macrolides; however, their use for these indications is less popular than it once was due to widespread development of resistance in the causative organisms.
This is a list of abbreviations used in medical prescriptions, including hospital orders (the patient-directed part of which is referred to as sig codes).This list does not include abbreviations for pharmaceuticals or drug name suffixes such as CD, CR, ER, XT (See Time release technology § List of abbreviations for those).
In pharmacology and medicine, dosage refers to the prescribed regimen for administering a medication or substance, encompassing the amount, frequency, and duration of use. [1] It is distinct from dose , which denotes a single, specific quantity of a drug or substance given at one time. [ 2 ]
In "double tetracycline labeling", a second dose is given 11–14 days after the first dose, and the amount of bone formed during that interval can be calculated by measuring the distance between the two fluorescent labels. [15] Tetracycline is also used as a biomarker in wildlife to detect consumption of medicine- or vaccine-containing baits. [16]
The term dosage form may also sometimes refer only to the pharmaceutical formulation of a drug product's constituent substances, without considering its final configuration as a consumable product (e.g., capsule, patch, etc.). Due to the somewhat ambiguous nature and overlap of these terms within the pharmaceutical industry, caution is ...
A hyclate (Latin: hyclas) is a pharmaceutical term for hydrochloride hemiethanolate hemihydrate [1] [2] (·HCl· 1 / 2 EtOH· 1 / 2 H 2 O), e.g. doxycycline hyclate. [ 3 ] [ 4 ] References
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