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Bifonazole (trade name Canespor among others [1]) is an imidazole antifungal drug used in form of ointments. It was patented in 1974 and approved for medical use in 1983. [ 2 ] There are also combinations with carbamide for the treatment of onychomycosis .
It can be taken by mouth or applied as a cream to the skin or in the vagina. [2] Common side effects when taken by mouth include nausea and itchiness. [2] When applied to the skin, common side effects include redness and a burning sensation. [2] In pregnancy, use on the skin or in the vagina is believed to be safe. [2]
Econazole is used as a cream to treat skin infections such as athlete's foot, tinea, pityriasis versicolor, ringworm, and jock itch.It is also sold in Canada under the brand name Ecostatin as vaginal ovules to treat vaginal thrush.
Miconazole, sold under the brand name Monistat among others, is an antifungal medication used to treat ring worm, pityriasis versicolor, and yeast infections of the skin or vagina. [2] It is used for ring worm of the body, groin (jock itch), and feet (athlete's foot). [2] It is applied to the skin or vagina as a cream or ointment. [2] [3]
Imiquimod, sold under the brand name Aldara among others, is a medication that acts as an immune response modifier that is used to treat genital warts, superficial basal cell carcinoma, and actinic keratosis. [4] Scientists at 3M's pharmaceuticals division discovered the drug and 3M obtained the first FDA approval in 1997. As of 2015, imiquimod ...
2-Methylimidazole (1) may be prepared via the Debus-Radziszewski imidazole synthesis, or from ethylenediamine and acetic acid, followed by treatment with lime, then Raney nickel. 2-Methylimidazole is nitrated to give 2-methyl-4(5)-nitroimidazole (2), which is in turn alkylated with ethylene oxide or 2-chloroethanol to give metronidazole (3 ...
Dithranol or anthralin (USAN and former BAN) is a hydroxyanthrone, anthracene derivative, and is used in medications applied to the skin of people with psoriasis.It is available as creams, ointment or pastes in 0.1 to 2% strengths (Drithocreme, Dithrocream, Zithranol-RR, Micanol, Psorlin, Dritho-Scalp, Anthraforte, Anthranol and Anthrascalp).
The plasma concentration reached a steady state on Day 5 of repeated administration study when nadifloxacin 1% cream was applied at 5 g twice daily to normal healthy individuals for a period of 7 days. The plasma concentration reached a peak of 4.1 ng/ml at 8 hours post-final dosing with an elimination half-life of 23.2 hours.
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