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  2. Domperidone - Wikipedia

    en.wikipedia.org/wiki/Domperidone

    There is a 2- to 3-fold accumulation in levels of domperidone with frequent repeated oral administration of domperidone (four times per day (every 5 hours) for 4 days). [9] The oral bioavailability of domperidone is somewhat increased, and time to peak slightly increased when it is taken with food and bioavailability is decreased by prior ...

  3. Ambroxol - Wikipedia

    en.wikipedia.org/wiki/Ambroxol

    This property led to the development of a lozenge containing 20 mg of ambroxol. Many state-of-the-art clinical studies [3] have demonstrated the efficacy of ambroxol in relieving pain in acute sore throat, with a rapid onset of action, with its effect lasting at least three hours. Ambroxol is also anti-inflammatory, reducing redness in a sore ...

  4. Deudomperidone - Wikipedia

    en.wikipedia.org/wiki/Deudomperidone

    [1] [2] [3] It acts as a selective dopamine D 2 and D 3 receptor antagonist and has peripheral selectivity. [ 2 ] [ 3 ] Deudomperidone is a deuterated form of domperidone , and it is suggested that deudomperidone may have improved efficacy , tolerability , and pharmacokinetics compared to domperidone.

  5. Dopamine antagonist - Wikipedia

    en.wikipedia.org/wiki/Dopamine_antagonist

    Dopamine receptor flow chart. Dopamine receptors are all G protein–coupled receptors, and are divided into two classes based on which G-protein they are coupled to. [1] The D 1-like class of dopamine receptors is coupled to Gα s/olf and stimulates adenylate cyclase production, whereas the D 2-like class is coupled to Gα i/o and thus inhibits adenylate cyclase production.

  6. Metformin - Wikipedia

    en.wikipedia.org/wiki/Metformin

    The US Food and Drug Administration (FDA) recommends avoiding the use of metformin in more severe chronic kidney disease, below the eGFR cutoff of 30 mL/minute/1.73 m 2. [94] Lactate uptake by the liver is diminished with metformin use because lactate is a substrate for hepatic gluconeogenesis , a process that metformin inhibits.

  7. Levosulpiride - Wikipedia

    en.wikipedia.org/wiki/Levosulpiride

    Levosulpiride, sold under the brand names Dislep and Sulpepta among others, is a dopamine antagonist medication which is used in the treatment of psychotic disorders like schizophrenia, major depressive disorder, nausea and vomiting, and gastroparesis.

  8. Rabeprazole - Wikipedia

    en.wikipedia.org/wiki/Rabeprazole

    Rabeprazole, sold under the brand name Aciphex, among others, is a medication that decreases stomach acid. [6] It is used to treat peptic ulcer disease, gastroesophageal reflux disease, and excess stomach acid production such as in Zollinger–Ellison syndrome. [6]

  9. Methyldopa - Wikipedia

    en.wikipedia.org/wiki/Methyldopa

    Methyldopa acts on alpha-2 adrenergic receptors, which are found on the pre synaptic nerve terminal. [1] This inhibits the release of norepinephrine from the presynaptic neuron. The S-enantiomer of methyldopa is a competitive inhibitor of the enzyme aromatic L -amino acid decarboxylase (LAAD), which converts L -DOPA into dopamine .