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  2. The Best Supplements for Men Over 50, According to ... - AOL

    www.aol.com/best-supplements-men-over-50...

    Zinc and vitamin D are also essential for bone health but have the added benefit for men over 50 by reducing the risk of erectile dysfunction, a condition commonly affecting men over age 40 ...

  3. Papain - Wikipedia

    en.wikipedia.org/wiki/Papain

    The enzyme is deacylated by a water molecule and releases the carboxy terminal portion of the peptide. In immunology, papain is known to cleave the Fc (crystallisable) portion of immunoglobulins (antibodies) from the Fab (antigen-binding) portion. Papain is a relatively heat-resistant enzyme, with an optimal temperature range of 60 to 70 °C. [9]

  4. Chymopapain - Wikipedia

    en.wikipedia.org/wiki/Chymopapain

    Chymopapain (EC 3.4.22.6, chymopapain A, chymopapain B, chymopapain S, brand name Chymodiactin) is a proteolytic enzyme isolated from the latex of papaya (Carica papaya).It is a cysteine protease which belongs to the papain-like protease (PLCP) group. [1]

  5. Caricain - Wikipedia

    en.wikipedia.org/wiki/Caricain

    Caricain can be assayed with Bz-ArgkNHPhNO2, kcat/Km being 187 M21 s21 at pH 6.8 and 40˚C. More sensitive substrates may employ a fluorometric leaving group, kcat/Km for the hydrolysis of Z-Phe-ArgkNHMec being 1.06 3 106 M21 s21 (pH 6.8, 40˚C). [5] The enzyme exhibits a broad pH-activity profile, with the optimum near 7.0.

  6. Actinidain - Wikipedia

    en.wikipedia.org/wiki/Actinidain

    Actinidain (EC 3.4.22.14, actinidin, Actinidia anionic protease, proteinase A2 of Actinidia chinensis) is a type of cysteine protease enzyme found in fruits including kiwifruit (genus Actinidia), pineapple, mango, banana, figs, and papaya. This enzyme is part of the peptidase C1 family of papain-like proteases. [1] [2] [3] [4]

  7. Papain-like protease - Wikipedia

    en.wikipedia.org/wiki/Papain-like_protease

    [3] [10] [9] Many papain-like protease enzymes function as monomers, though a few, such as cathepsin C (Dipeptidyl-peptidase I), are homotetramers. The mature monomer structure is characteristically divided into two lobes or subdomains, known as the L-domain ( N-terminal ) and the R-domain ( C-terminal ), where the active site is located ...

  8. Benign prostatic hyperplasia - Wikipedia

    en.wikipedia.org/wiki/Benign_prostatic_hyperplasia

    As of 2019, about 94 million men aged 40 years and older are affected globally. [3] BPH typically begins after the age of 40. [1] The prevalence of clinically diagnosed BPH peaks at 24% in men aged 75–79 years. [3] Based on autopsy studies, half of males aged 50 and over are affected, and this figure climbs to 80% after the age of 80. [3]

  9. Glutamate carboxypeptidase II - Wikipedia

    en.wikipedia.org/wiki/Glutamate_carboxypeptidase_II

    In human prostate cancer, the higher expressing tumors are associated with quicker time to progression and a greater percentage of patients suffering relapse. [ 21 ] [ 22 ] In vitro studies using prostate and breast cancer cell lines with decreased PSMA levels showed a significant decrease in the proliferation, migration, invasion, adhesion and ...

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