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Chloroquine is an antiparasitic medication that treats malaria. It works by increasing the levels of haeme in the blood, a substance toxic to the malarial parasite. This kills the parasite and stops the infection from spreading. [1]
Chloroquine has been used in the treatment of malaria for many years and no abortifacient or teratogenic effects have been reported during this time; therefore, it is considered very safe to use during pregnancy.
On 1 April 2020, the European Medicines Agency (EMA) issued guidance that chloroquine and hydroxychloroquine are only to be used in clinical trials or emergency use programs. [43] On 9 April 2020, the National Institutes of Health began the first clinical trial to assess whether hydroxychloroquine is safe and effective to treat COVID-19.
Chloroquine retinopathy is a form of toxic retinopathy (damage of the retina) caused by the drugs chloroquine or hydroxychloroquine, which are sometimes used in the treatment of autoimmune disorders such as rheumatoid arthritis and systemic lupus erythematosus. This eye toxicity limits long-term use of the drugs. [3]
For short-term treatment of acute malaria, adverse effects can include abdominal cramps, diarrhea, heart problems, reduced appetite, headache, nausea and vomiting. [3] Other adverse effects noted with short-term use of Hydroxychloroquine include low blood sugar and QT interval prolongation. [19] Idiosyncratic hypersensitivity reactions have ...
Is Ozempic Safe to Take Long-Term? Ozempic (semaglutide) is approved by the U.S. Food and Drug Administration (FDA) for managing blood sugar levels in type 2 diabetes patients.
As one can see, it would take many days for the total amount of drug within the body to come close to 1 gram (1000 mg) and achieve its full therapeutic effect. For a drug such as this, a doctor might prescribe a loading dose of one gram to be taken on the first day. That immediately gets the drug's concentration in the body up to the ...
Doctors explain why the drug semaglutide needs to be taken for the long term and if it's safe. ... is usually given to new patients to ease into the treatment with the least amount of side effects.